Aripiprazole and Atarax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aripiprazole (aripiprazole) and Atarax (hydroxyzine hydrochloride). Common drug interactions include injection site rash among females and faecal vomiting among males.

The phase IV clinical study analyzes what interactions people have when they take Aripiprazole and Atarax. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Aripiprazole?

Aripiprazole has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 39,143 Aripiprazole users. Check the latest studies of Aripiprazole.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.



On Jul, 10, 2026

62 people who take Aripiprazole and Atarax together, and have interactions are studied.

Aripiprazole and Atarax drug interactions.

What are the common drug interactions of Aripiprazole and Atarax, by gender? *:

female:

  1. Injection site rash
  2. Injection site urticaria (rash of round, red welts on the skin at injection site)
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally)
  4. Neutropenia (an abnormally low number of neutrophils)
  5. Overdose
  6. Restless legs syndrome (a powerful urge to move your legs)
  7. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  8. Urinary tract infection
  9. Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)
  10. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)

male:

  1. Faecal vomiting (faeces in vomiting)
  2. Intestinal obstruction
  3. Proteinuria (presence of protein in the urine)
  4. Weight decreased
  5. Psychotic disorder
  6. Abnormal behaviour
  7. Acidosis (build-up of carbon dioxide in the blood)
  8. Arthralgia (joint pain)
  9. Bradycardia (abnormally slow heart action)
  10. Burning sensation

What are the common drug interactions of Aripiprazole and Atarax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)
  2. Feeling hot
  3. Limb discomfort (discomfort in leg)
  4. Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
  5. Syncope (loss of consciousness with an inability to maintain postural tone)
  6. Visual impairment
  7. Suicide attempt

20-29:

  1. Psychotic disorder
  2. Abnormal behaviour
  3. Bradycardia (abnormally slow heart action)
  4. Electrocardiogram qt prolonged

30-39:

  1. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  2. Dyskinesia (abnormality or impairment of voluntary movement)
  3. Abnormal behaviour
  4. Aggression
  5. Aphasia (damage to the parts of the brain that control language)
  6. Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
  7. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
  8. Disinhibition (loss of inhibition)
  9. Hypophagia (reduced food intake)
  10. Poriomania (unconscious tendency to walk away from home)

40-49:

  1. Faecal vomiting (faeces in vomiting)
  2. Intestinal obstruction
  3. Mood altered (changes in mood)
  4. Acidosis (build-up of carbon dioxide in the blood)
  5. Drug ineffective
  6. Folliculitis (infection of hair root)
  7. Multi-organ failure (multisystem organ failure)
  8. Overdose
  9. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  10. Subdural haematoma (blood collects between the skull and the surface of the brain)

50-59:

  1. Personality change
  2. Pyrexia (fever)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Injection site erythema (redness at injection site)
  6. Injection site pruritus (severe itching at injection site)
  7. Injection site rash
  8. Injection site urticaria (rash of round, red welts on the skin at injection site)
  9. Biliary tract infection
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

60+:

  1. Loss of consciousness
  2. Drug hypersensitivity
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally)
  4. Restless legs syndrome (a powerful urge to move your legs)
  5. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

What are the existing conditions these people have? *

  1. Bipolar Disorder (mood disorder): 9 people, 14.52%
  2. Itching: 7 people, 11.29%
  3. Pain: 6 people, 9.68%
  4. Autism Spectrum Disorder (developmental disabilities that can cause significant social, communication and behavioural challenges): 6 people, 9.68%
  5. Sleep Apnea Syndrome: 5 people, 8.06%
  6. High Blood Pressure: 5 people, 8.06%
  7. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 4 people, 6.45%
  8. Insomnia (sleeplessness): 4 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Aripiprazole and Atarax:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Aripiprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Atarax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aripiprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Atarax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on aripiprazole and hydroxyzine hydrochloride (the active ingredients of Aripiprazole and Atarax, respectively), and Aripiprazole and Atarax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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