Aripiprazole and Nexplanon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aripiprazole (aripiprazole) and Nexplanon (etonogestrel). Common drug interactions include intermenstrual bleeding among females.

The phase IV clinical study analyzes what interactions people have when they take Aripiprazole and Nexplanon. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Aripiprazole?

Aripiprazole has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 39,143 Aripiprazole users. Check the latest studies of Aripiprazole.

What is Nexplanon?

Nexplanon has active ingredients of etonogestrel. It is often used in birth control. eHealthMe is studying from 46,431 Nexplanon users. Check the latest studies of Nexplanon.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

49 people who take Aripiprazole and Nexplanon together, and have interactions are studied.

Aripiprazole and Nexplanon drug interactions.

What are the common drug interactions of Aripiprazole and Nexplanon, by gender? *:

female:

Intermenstrual bleeding
Abortion spontaneous (naturally occurring miscarriage)
Agitation (state of anxiety or nervous excitement)
Confusional state
Delusion (a false belief or opinion)
Depressive symptom
Drug ineffective
Dystonia (abnormal muscle tone)
Hallucination, visual (seeing things that aren't there)
Impulsive behaviour

male:

n/a

What are the common drug interactions of Aripiprazole and Nexplanon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Intermenstrual bleeding
Abortion spontaneous (naturally occurring miscarriage)
Maternal exposure during pregnancy (use of substance during pregnancy)
Pregnancy with implant contraceptive
Unintended pregnancy (unwanted pregnancies as well as those that are mistimed)
Pregnancy on contraceptive
Pregnancy with contraceptive device
Metrorrhagia (uterine bleeding at irregular intervals)
Complication of device insertion
Implant site abscess

20-29:

Abortion spontaneous (naturally occurring miscarriage)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Post abortion haemorrhage
Pregnancy with implant contraceptive
Unintended pregnancy (unwanted pregnancies as well as those that are mistimed)
Delirium (wild excitement)
Dysmenorrhoea (painful menstruation)
Headache (pain in head)
Hypomenorrhoea (a diminution of the menstrual flow or a shortening of the duration of menstruation)
Intermenstrual bleeding

30-39:

Affect lability (emotional incontinence)
Agitation (state of anxiety or nervous excitement)
Insomnia (sleeplessness)
Suicidal ideation
Weight increased
Abnormal behaviour
Sleep disorder
Arthralgia (joint pain)
Axillary pain
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 25 people, 51.02%
Seasonal Allergy (allergic condition due to certain season): 24 people, 48.98%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 7 people, 14.29%
Negative Thoughts: 7 people, 14.29%
Ill-Defined Disorder: 7 people, 14.29%
Respiration Abnormal (abnormal breathing process): 5 people, 10.20%
Insomnia (sleeplessness): 5 people, 10.20%
Sedation: 4 people, 8.16%
Personality Disorder: 4 people, 8.16%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 4 people, 8.16%

* Approximation only. Some reports may have incomplete information.

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