Arixtra and Naproxen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Arixtra (fondaparinux sodium) and Naproxen (naproxen). Common drug interactions include emotional distress among females and gastroduodenal ulcer among males.

The phase IV clinical study analyzes what interactions people have when they take Arixtra and Naproxen. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Arixtra?

Arixtra has active ingredients of fondaparinux sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 9,830 Arixtra users. Check the latest studies of Arixtra.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.

On Jul, 16, 2026

19 people who take Arixtra and Naproxen together, and have interactions are studied.

What are the common drug interactions of Arixtra and Naproxen, by gender? *:

female:

Emotional distress
Injury
Pulmonary embolism (blockage of the main artery of the lung)
Acute hepatic failure
Anxiety
Axillary vein thrombosis (formation of a blood clot in axillary vein)
Cardiac disorder
Post procedural complication
Pyrexia (fever)
Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)

male:

Gastroduodenal ulcer
Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Toothache (tooth pain)
Varices oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach)
Pulmonary embolism (blockage of the main artery of the lung)
Device related infection
Pyrexia (fever)
Biliary tract disorder
Cardiac arrest
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the common drug interactions of Arixtra and Naproxen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cardiac disorder
Emotional distress
Injury
Pulmonary embolism (blockage of the main artery of the lung)

30-39:

Axillary vein thrombosis (formation of a blood clot in axillary vein)
Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

40-49:

n/a

50-59:

Device related infection
Acute hepatic failure
Pyrexia (fever)

60+:

Gastroduodenal ulcer
Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Pulmonary embolism (blockage of the main artery of the lung)
Pyrexia (fever)
Biliary tract disorder
Cardiac arrest
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematemesis (vomiting of blood)
Melaena (the passage of black, tarry stools)
Varices oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach)

What are the existing conditions these people have? *

Back Pain: 12 people, 63.16%
Infarction (obstruction of the blood supply to an organ or region of tissue): 11 people, 57.89%
Multiple Myeloma (cancer of the plasma cells): 3 people, 15.79%
Adverse Event: 2 people, 10.53%
Stress And Anxiety: 1 person, 5.26%
Pvt: 1 person, 5.26%
Premenstrual Syndrome: 1 person, 5.26%
Non-Hodgkin's Lymphoma Refractory (refractory malignant (cancer) cells form in the lymph system): 1 person, 5.26%
Nausea (feeling of having an urge to vomit): 1 person, 5.26%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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