Artane and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Artane (trihexyphenidyl hydrochloride) and Acetaminophen (acetaminophen). Common drug interactions include convulsion among females and dyskinesia among males.

The phase IV clinical study analyzes what interactions people have when they take Artane and Acetaminophen. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Artane?

Artane has active ingredients of trihexyphenidyl hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 3,619 Artane users. Check the latest studies of Artane.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

On Jul, 11, 2026

35 people who take Artane and Acetaminophen together, and have interactions are studied.

Artane and Acetaminophen drug interactions.

What are the common drug interactions of Artane and Acetaminophen, by gender? *:

female:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Deformity (disfigurement)
Dementia (madness)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Dislocation of joint prosthesis
Dizziness
Drug hypersensitivity
Dyskinesia (abnormality or impairment of voluntary movement)

male:

Dyskinesia (abnormality or impairment of voluntary movement)
Abnormal dreams
On and off phenomenon
Tooth infection
Urinary tract infection
Abnormal behaviour
Acute respiratory failure
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Angiopathy (generic term for a disease of the blood vessels)
Anxiety

What are the common drug interactions of Artane and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

Drug ineffective

2-9:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Cytolytic hepatitis (dissolution or destruction of a liver cell)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Tooth infection
Respiratory distress (difficulty in breathing)

10-19:

Somnolence (a state of near-sleep, a strong desire for sleep)
Speech disorder

20-29:

Abdominal discomfort
Abdominal distension
Activities of daily living impaired
Akathisia (a movement disorder characterized by a feeling of inner restlessness)
Anxiety
Asthenia (weakness)
Bruxism (habitual grinding of the teeth, typically during sleep)
Cardiac arrest
Deformity (disfigurement)
Depression

30-39:

Lung disorder (lung disease)
Night sweats (sweating in night)
Obesity (having too much body fat)
Productive cough
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Pulmonary haemorrhage (acute bleeding from the lung)
Pulmonary oedema (fluid accumulation in the lungs)
Rash
Scar
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

40-49:

Cholecystitis acute (rapid infection of gallbladder)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Pancreatitis (inflammation of pancreas)
Pancreatitis acute (sudden inflammation of pancreas)
Pancreatitis chronic (chronic inflammation of pancreas)
Type 2 diabetes mellitus
Vision blurred

50-59:

Nausea (feeling of having an urge to vomit)
Staphylococcal infection (an infection with staphylococcus bacteria)
Vomiting
Alopecia (absence of hair from areas of the body)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anal fissure
Anxiety
Arthralgia (joint pain)
Asthma
Back pain

60+:

Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)
Acute circulatory failure (shock)
Blood pressure decreased
Hyperkalaemia (damage to or disease of the kidney)
Oliguria (not enough urine)
Pulmonary oedema (fluid accumulation in the lungs)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Oropharyngeal pain
Sensation of foreign body

What are the existing conditions these people have? *

Tongue Biting: 5 people, 14.29%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 5 people, 14.29%
Movement - Uncontrolled Or Slow: 5 people, 14.29%
Encephalitis (inflammation of the brain): 5 people, 14.29%
Sedation: 4 people, 11.43%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 8.57%
Agitation (state of anxiety or nervous excitement): 3 people, 8.57%
Respiratory Tract Infection: 3 people, 8.57%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 3 people, 8.57%
Muscle Spasms (muscle contraction): 3 people, 8.57%

* Approximation only. Some reports may have incomplete information.

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