Asacol and Epivir drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Asacol (mesalamine) and Epivir (lamivudine). Common drug interactions include dyspnoea among females and foot fracture among males.
The phase IV clinical study analyzes what interactions people have when they take Asacol and Epivir. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Asacol?
Asacol has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 20,618 Asacol users. Check the latest studies of Asacol.
What is Epivir?
Epivir has active ingredients of lamivudine. It is often used in hiv infection. eHealthMe is studying from 16,870 Epivir users. Check the latest studies of Epivir.
13 people who take Asacol and Epivir together, and have interactions are studied.

What are the common drug interactions of Asacol and Epivir, by gender? *:
female:
- Dyspnoea (difficult or laboured respiration)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Chronic kidney disease
- Emotional distress
- Eye pruritus (eye itching)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Osteoporosis (bones weak and more likely to break)
- Pain
- Pneumonia
male:
- Foot fracture
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Osteoporosis (bones weak and more likely to break)
- Pain
- Renal failure (kidney dysfunction)
- Rib fracture
- Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Oedema lower limb (fluid collection in tissue of lower leg)
What are the common drug interactions of Asacol and Epivir, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Lymphadenopathy (disease or enlargement of lymph nodes)
- Oedema lower limb (fluid collection in tissue of lower leg)
- Abdominal pain upper
- Activated partial thromboplastin time prolonged
- Confusion
- Dyspnoea (difficult or laboured respiration)
- Eosinophil count increased
- Headache (pain in head)
- Hepatic failure (liver failure)
- Hepatitis (inflammation of the liver)
40-49:
n/a
50-59:
- Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
- Depression
- Inflammatory bowel disease
- Injury
- Mean platelet volume decreased (less than normal average size of platelet cells in blood)
- Oedema peripheral (superficial swelling)
- Platelet count decreased
- White blood cell count decreased
60+:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Hand fracture
- Hip fracture
- Osteonecrosis (death of bone)
- Renal failure (kidney dysfunction)
- Rib fracture
- Dyspnoea (difficult or laboured respiration)
- Eye pruritus (eye itching)
- Pneumonia
What are the existing conditions these people have? *
- Hiv Infection: 5 people, 38.46%
- Viral Infection: 2 people, 15.38%
- Cardiac Failure Congestive: 2 people, 15.38%
- Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 2 people, 15.38%
- Dementia (madness): 2 people, 15.38%
- Constipation: 2 people, 15.38%
- Colitis (inflammation of colon): 2 people, 15.38%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 15.38%
- Breast Cancer: 2 people, 15.38%
- Diabetes: 2 people, 15.38%
* Approximation only. Some reports may have incomplete information.
Do you take Asacol and Epivir?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Asacol and Epivir:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Asacol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Epivir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Asacol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Epivir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on mesalamine and lamivudine (the active ingredients of Asacol and Epivir, respectively), and Asacol and Epivir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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