Astepro and Niaspan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Astepro (azelastine hydrochloride) and Niaspan (niacin). Common drug interactions include dyspnoea among females and flushing among males.

The phase IV clinical study analyzes what interactions people have when they take Astepro and Niaspan. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.

What is Astepro?

Astepro has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 3,336 Astepro users. Check the latest studies of Astepro.

What is Niaspan?

Niaspan has active ingredients of niacin. It is often used in high blood cholesterol. eHealthMe is studying from 45,453 Niaspan users. Check the latest studies of Niaspan.

On Jul, 12, 2026

31 people who take Astepro and Niaspan together, and have interactions are studied.

What are the common drug interactions of Astepro and Niaspan, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Pruritus (severe itching of the skin)
Anaphylactic reaction (serious allergic reaction)
Feeling hot
Flushing (the warm, red condition of human skin)
Chest discomfort
Dysphonia (speech disorder attributable to a disorder of phonation)
Glossodynia (a burning or painful sensation in the tongue)
Hypersensitivity
Swollen tongue (swelling of tongue)

male:

Flushing (the warm, red condition of human skin)
Feeling hot
Pain
Penile haematoma (localized collection of blood outside the blood vessels on penis)
Penile swelling
Gout (uric acid crystals building up in the body)
Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Asthma
Back pain

What are the common drug interactions of Astepro and Niaspan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anaphylactic reaction (serious allergic reaction)
Abdominal pain
Diarrhoea
Dizziness
Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)
Hypertension (high blood pressure)
Pruritus generalised (generalized itching)

50-59:

Anxiety
Drug effect increased
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Feeling hot
Flushing (the warm, red condition of human skin)
Insomnia (sleeplessness)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)

60+:

Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Dysphagia (a condition in which swallowing is difficult or painful)
Chest discomfort
Dysphonia (speech disorder attributable to a disorder of phonation)
Dyspnoea (difficult or laboured respiration)
Glossodynia (a burning or painful sensation in the tongue)
Hypersensitivity
Swollen tongue (swelling of tongue)
Burning sensation
Choking (mechanical obstruction of the flow of air from the environment into the lungs)

What are the existing conditions these people have? *

Parkinson's Disease: 4 people, 12.90%
High Blood Pressure: 4 people, 12.90%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 9.68%
Asthma: 3 people, 9.68%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 6.45%
Stress And Anxiety: 2 people, 6.45%
Irritable Bowel Syndrome: 2 people, 6.45%
Hypersensitivity: 2 people, 6.45%
High Density Lipoprotein Decreased: 2 people, 6.45%
Dyspnea (difficult or laboured breathing): 2 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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