Isoniazid and Premarin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Isoniazid (isoniazid) and Premarin (estrogens, conjugated). Common drug interactions include bronchitis among females.
The phase IV clinical study analyzes what interactions people have when they take Isoniazid and Premarin. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.
What is Isoniazid?
Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. eHealthMe is studying from 20,174 Isoniazid users. Check the latest studies of Isoniazid.
What is Premarin?
Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.
36 people who take Isoniazid and Premarin together, and have interactions are studied.

What are the common drug interactions of Isoniazid and Premarin, by gender? *:
female:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Influenza
- Weight decreased
- Abdominal pain upper
- Arthralgia (joint pain)
- Blood bilirubin increased
- Decreased appetite
- Drug ineffective
- Haematocrit decreased
- Migraine (headache)
male:
n/a
What are the common drug interactions of Isoniazid and Premarin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Abdominal pain
- Asthenia (weakness)
- Circulatory collapse
- Constipation
- Cough
- Diarrhoea
- Difficulty in walking
- Dizziness
- Drug dependence
- Drug ineffective
40-49:
- Dizziness (excl vertigo)
- Hepatitis (inflammation of the liver)
- Rigors (an episode of shaking or exaggerated shivering)
50-59:
- Platelet count increased
- Pruritus (severe itching of the skin)
- Psoriasis (immune-mediated disease that affects the skin)
- Rash
- Sputum abnormal
- Sputum discoloured
- Throat tightness
- Tooth abscess (pus formation in tooth)
- Tuberculosis of peripheral lymph nodes (a bacterial infection of superficial lymph node by mycobacterium tuberculosis)
- Upper respiratory tract infection
60+:
- Pain in extremity
- Arthralgia (joint pain)
- Migraine (headache)
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Myalgia (muscle pain)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Tooth abscess (pus formation in tooth)
- Upper respiratory tract infection
- Abdominal pain upper
- Abnormal faeces (abnormal stool)
What are the existing conditions these people have? *
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 16 people, 44.44%
- Sleep Apnea Syndrome: 4 people, 11.11%
- Nausea (feeling of having an urge to vomit): 4 people, 11.11%
- Muscle Aches (muscle pain): 4 people, 11.11%
- Dry Eyes (lack of adequate tears): 4 people, 11.11%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 5.56%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Isoniazid and Premarin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Isoniazid and Premarin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Isoniazid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Premarin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Isoniazid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Premarin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ganguly, R. J., Abraham, R. R., Prasad, R., & Rao, B. C, "Hyperglycaemia induced by isoniazid preventive therapy", Journal of Family Medicine and Primary Care, 2018 Jan .
- Ganguly, R. J., Abraham, R. R., Prasad, R., & Rao, B. C, "Hyperglycaemia induced by isoniazid preventive therapy", Journal of Family Medicine and Primary Care, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on isoniazid and estrogens, conjugated (the active ingredients of Isoniazid and Premarin, respectively), and Isoniazid and Premarin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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