Ativan and Norpramin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ativan (lorazepam) and Norpramin (desipramine hydrochloride). Common drug interactions include systemic inflammatory response syndrome among females and diabetes mellitus non-insulin-dependent among males.

The phase IV clinical study analyzes what interactions people have when they take Ativan and Norpramin. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Ativan?

Ativan has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 78,506 Ativan users. Check the latest studies of Ativan.

What is Norpramin?

Norpramin has active ingredients of desipramine hydrochloride. It is often used in depression. eHealthMe is studying from 272 Norpramin users. Check the latest studies of Norpramin.

On Jul, 20, 2026

20 people who take Ativan and Norpramin together, and have interactions are studied.

What are the common drug interactions of Ativan and Norpramin, by gender? *:

female:

Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Confusional state
Dizziness
Hepatitis (inflammation of the liver)
Abdominal discomfort
Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
Asthenia (weakness)
Cardiac arrest
Chest discomfort

male:

Diabetes mellitus non-insulin-dependent
Erectile dysfunction
Vomiting
Arthralgia (joint pain)
Blood glucose increased
Blood potassium increased
Chronic hepatitis (long lasting inflammation of liver)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Pancreatitis acute (sudden inflammation of pancreas)
Rash

What are the common drug interactions of Ativan and Norpramin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Alcohol withdrawal syndrome
Drug screen positive
Hepatitis (inflammation of the liver)
Nausea (feeling of having an urge to vomit)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Vomiting

40-49:

Diabetes mellitus non-insulin-dependent
Erectile dysfunction
Neuropathy peripheral (surface nerve damage)
Pruritus generalised (generalized itching)
Confusional state
Electrocardiogram st segment elevation
Rash generalised (rash on most of body parts)
Arthralgia (joint pain)
Blood glucose increased
Blood potassium increased

50-59:

Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
Dental caries
Dizziness
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Fall
Gingivitis (inflammation of gums)
Hip arthroplasty
Vision blurred
Wrist fracture

60+:

Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Abdominal discomfort
Asthenia (weakness)
Cardiac arrest
Chest discomfort
Dizziness
Dysgeusia (disorder of the sense of taste)
Hypotension (abnormally low blood pressure)
Lung neoplasm malignant (cancer tumour of lung)

What are the existing conditions these people have? *

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 4 people, 20.00%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 3 people, 15.00%
Pain: 2 people, 10.00%
Osteoporosis (bones weak and more likely to break): 2 people, 10.00%
High Blood Pressure: 1 person, 5.00%
Dry Eyes (lack of adequate tears): 1 person, 5.00%
Facial Pain: 1 person, 5.00%
Fever: 1 person, 5.00%
Fibromyalgia (a long-term condition which causes pain all over the body): 1 person, 5.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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