Augmentin '125' and Acetaminophen and codeine phosphate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin '125' (amoxicillin; clavulanate potassium) and Acetaminophen and codeine phosphate (acetaminophen; codeine phosphate). Common drug interactions include cardiac failure among females and pruritus among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin '125' and Acetaminophen and codeine phosphate. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin '125'?

Augmentin '125' has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 10,452 Augmentin '125' users. Check the latest studies of Augmentin '125'.

What is Acetaminophen and codeine phosphate?

Acetaminophen and codeine phosphate has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 3,220 Acetaminophen and codeine phosphate users. Check the latest studies of Acetaminophen and codeine phosphate.

On Jul, 08, 2026

23 people who take Augmentin '125' and Acetaminophen and codeine phosphate together, and have interactions are studied.

Augmentin '125' and Acetaminophen and codeine phosphate drug interactions.

What are the common drug interactions of Augmentin '125' and Acetaminophen And Codeine Phosphate, by gender? *:

female:

Cardiac failure
Cellulitis (infection under the skin)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Tooth infection
Calciphylaxis (is a syndrome with vascular calcium accumulation)
Cardiovascular disorder (heart diseases)
Chest pain
Confusion
Diarrhoea

male:

Pruritus (severe itching of the skin)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Skin disorder (skin disease)
Skin exfoliation (removal of the oldest dead skin cells)
Skin lesion
Toxic skin eruption (skin breakdown due to toxic substance)
Urinary tract infection staphylococcal
Weight increased
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the common drug interactions of Augmentin '125' and Acetaminophen And Codeine Phosphate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Pruritus (severe itching of the skin)
Rash
Vomiting

20-29:

n/a

30-39:

Blood creatine phosphokinase increased
Cardiovascular disorder (heart diseases)
Chest pain
Coma (state of unconsciousness lasting more than six hours)
Confusion
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Crying
Dyspnoea (difficult or laboured respiration)
Fall
Malaise (a feeling of general discomfort or uneasiness)

40-49:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Tardive dyskinesia (a disorder that involves involuntary movements)

50-59:

Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Erythema (redness of the skin)
Generalised erythema (redness of the skin all over the body)
Leukocytosis (increased white blood cells)
Pruritus (severe itching of the skin)
Purpura (purplish discoloration of the skin)
Pyrexia (fever)

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cellulitis (infection under the skin)
Hypokalaemia (low potassium)
Hypoprothrombinaemia (blood disorder in which a deficiency of prothrombin (factor ii) results in impaired blood clotting)
International normalised ratio increased
Orthopnoea (shortness of breath (dyspnea) when lying down)
Pneumonia
Sinus bradycardia (an unusually slow heartbeat due to heart disease)
Syncope (loss of consciousness with an inability to maintain postural tone)
Tongue dry

What are the existing conditions these people have? *

Toothaches (tooth pain): 4 people, 17.39%
Depression: 4 people, 17.39%
High Blood Pressure: 4 people, 17.39%
Dry Skin: 2 people, 8.70%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 2 people, 8.70%
Candidiasis (candidiasis or thrush is a fungal infection): 2 people, 8.70%
Colon Cancer: 2 people, 8.70%
Constipation: 2 people, 8.70%
Dermatitis Acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis): 2 people, 8.70%
Diarrhea: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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