Augmentin '125' and Glucovance drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Augmentin '125' (amoxicillin; clavulanate potassium) and Glucovance (glyburide; metformin hydrochloride). Common drug interactions include cellulitis among females and anaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Augmentin '125' and Glucovance. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.
What is Augmentin '125'?
Augmentin '125' has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 10,452 Augmentin '125' users. Check the latest studies of Augmentin '125'.
What is Glucovance?
Glucovance has active ingredients of glyburide; metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 6,302 Glucovance users. Check the latest studies of Glucovance.
38 people who take Augmentin '125' and Glucovance together, and have interactions are studied.

What are the common drug interactions of Augmentin '125' and Glucovance, by gender? *:
female:
- Cellulitis (infection under the skin)
- Dyspnoea (difficult or laboured respiration)
- Migraine (headache)
- Oral candidiasis (fungal infection of mouth)
- Osteomyelitis (infection of bone)
- Osteonecrosis of jaw (death of bone of jaw)
- Pain
- Pain in jaw
- Pyrexia (fever)
- Rash
male:
- Anaemia (lack of blood)
- Anxiety
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Weight decreased
- Back pain
- Fatigue (feeling of tiredness)
- Asthma
- Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
- Confusional state
What are the common drug interactions of Augmentin '125' and Glucovance, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal pain
- Abscess neck (neck abscesses)
- Accommodation disorder
- Adenomyosis (presence of ectopic glandular tissue found in muscle)
- Altered state of consciousness (altered state of mind)
- Altered visual depth perception
- Anaemia (lack of blood)
- Aphasia (damage to the parts of the brain that control language)
- Arthralgia (joint pain)
- Arthropathy
50-59:
- Hepatitis (inflammation of the liver)
- Abdominal pain upper
- Alanine aminotransferase increased
- Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
- Aspartate aminotransferase increased
- Blood alkaline phosphatase increased
- Blood pressure decreased
- Bradycardia (abnormally slow heart action)
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
- Gamma-glutamyltransferase increased
60+:
- Anxiety
- Headache (pain in head)
- Anaemia (lack of blood)
- Asthenia (weakness)
- Dizziness
- Hypoaesthesia (reduced sense of touch or sensation)
- Loss of consciousness
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Depression
What are the existing conditions these people have? *
- Metastases To Bone (cancer spreads to bone): 18 people, 47.37%
- High Blood Pressure: 18 people, 47.37%
- Depression: 18 people, 47.37%
- Breast Cancer: 18 people, 47.37%
- Bone Pain: 18 people, 47.37%
- Resorption Bone Increased: 4 people, 10.53%
- Osteolysis (dissolution of bone): 4 people, 10.53%
* Approximation only. Some reports may have incomplete information.
Do you take Augmentin '125' and Glucovance?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Augmentin '125' (10,452 reports)
- Glucovance (6,302 reports)
Browse all drug interactions of Augmentin '125' and Glucovance:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Augmentin '125':
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Glucovance:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Augmentin '125' and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Glucovance and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium and glyburide; metformin hydrochloride (the active ingredients of Augmentin '125' and Glucovance, respectively), and Augmentin '125' and Glucovance (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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