Augmentin '500' and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin '500' (amoxicillin; clavulanate potassium) and Acetaminophen (acetaminophen). Common drug interactions include breast cancer recurrent among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin '500' and Acetaminophen. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin '500'?

Augmentin '500' has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 509 Augmentin '500' users. Check the latest studies of Augmentin '500'.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

On Jul, 15, 2026

32 people who take Augmentin '500' and Acetaminophen together, and have interactions are studied.

Augmentin '500' and Acetaminophen drug interactions.

What are the common drug interactions of Augmentin '500' and Acetaminophen, by gender? *:

female:

Breast cancer recurrent
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Chest pain
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Confusional state
Constipation
Decreased interest
Depressed mood
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Diaphragmatic hernia (defect or hole in the diaphragm that allows the abdominal contents to move into the chest cavity)

male:

Anaemia (lack of blood)
Asthenia (weakness)
Small intestinal stenosis (abnormal narrowing of small intestine)
Thrombosis (formation of a blood clot inside a blood vessel)
Cardiac arrest
Febrile neutropenia (fever with reduced white blood cells)
Muscle abscess (pus in muscle)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia
Renal failure acute (rapid kidney dysfunction)

What are the common drug interactions of Augmentin '500' and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Cellulitis (infection under the skin)
Upper respiratory tract infection
Lymphadenitis (inflammation or enlargement of a lymph node)
Lymphadenopathy (disease or enlargement of lymph nodes)
Pyrexia (fever)

10-19:

Acute hepatic failure
Encephalopathy (functioning of the brain is affected by some agent or condition)
Hepatic failure (liver failure)
Hepatitis (inflammation of the liver)
Hepatotoxicity (chemical-driven liver damage)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Liver transplant
Nausea (feeling of having an urge to vomit)
Pruritus (severe itching of the skin)

20-29:

Abdominal pain
Chest pain
Cholecystitis chronic (long lasting infection of gallbladder)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Gallbladder disorder
Pulmonary embolism (blockage of the main artery of the lung)
Rash

30-39:

Hyperkeratosis (thickening of the outer layer of the skin)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypertension (high blood pressure)
Hypokalaemia (low potassium)
Hypophagia (reduced food intake)
Impaired gastric emptying
Insomnia (sleeplessness)
Intervertebral disc degeneration (spinal disc degeneration)
Intervertebral disc protrusion (spinal disc protrusion)
Loose tooth

40-49:

Ataxia (loss of full control of bodily movements)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatitis acute
Hepatocellular damage (liver damage)
Hepatomegaly (abnormal enlargement of the liver)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pulmonary embolism (blockage of the main artery of the lung)
Splenomegaly (enlargement of spleen)

50-59:

Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Ascites (accumulation of fluid in the abdominal cavity)
Haematemesis (vomiting of blood)
Hyperkalaemia (damage to or disease of the kidney)
Jaundice cholestatic
Malignant neoplasm progression (cancer tumour came back)
Metastases to central nervous system (cancer spreads to central nervous system)
Neutropenia (an abnormally low number of neutrophils)
Oedema peripheral (superficial swelling)
Renal failure acute (rapid kidney dysfunction)

60+:

Cardiac arrest
Anaemia (lack of blood)
Pneumonia
Renal failure (kidney dysfunction)
Thrombocytopenia (decrease of platelets in blood)
Acute respiratory failure
Bladder dilatation
Dyskinesia (abnormality or impairment of voluntary movement)
Hallucination, visual (seeing things that aren't there)
Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

Fever: 4 people, 12.50%
Lymphocytic Leukaemia (a type of cancer in which the bone marrow makes too many lymphocytes): 3 people, 9.38%
Metastases To Bone (cancer spreads to bone): 2 people, 6.25%
High Blood Pressure: 2 people, 6.25%
Breast Cancer: 2 people, 6.25%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Augmentin '500' and Acetaminophen?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously