Augmentin and Fludarabine phosphate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Fludarabine phosphate (fludarabine phosphate). Common drug interactions include febrile neutropenia among females and pneumonia among males.
The phase IV clinical study analyzes what interactions people have when they take Augmentin and Fludarabine phosphate. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.
What is Augmentin?
Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.
What is Fludarabine phosphate?
Fludarabine phosphate has active ingredients of fludarabine phosphate. eHealthMe is studying from 12,840 Fludarabine phosphate users. Check the latest studies of Fludarabine phosphate.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
31 people who take Augmentin and Fludarabine phosphate together, and have interactions are studied.

What are the common drug interactions of Augmentin and Fludarabine Phosphate, by gender? *:
female:
- Febrile neutropenia (fever with reduced white blood cells)
- Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
- Back pain
- Bone marrow failure
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Dizziness
- Drug eruption (adverse drug reaction of the skin)
- Headache (pain in head)
- Hypoaesthesia (reduced sense of touch or sensation)
- Nausea (feeling of having an urge to vomit)
male:
- Pneumonia
- Renal failure acute (rapid kidney dysfunction)
- Acute myocardial infarction (acute heart attack)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Bradycardia (abnormally slow heart action)
- Enterococcal infection
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Multi-organ failure (multisystem organ failure)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
What are the common drug interactions of Augmentin and Fludarabine Phosphate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Abdominal pain
- Anaemia (lack of blood)
- Constipation
- Cough
- Device related infection
- Electrocardiogram qt prolonged
- Face oedema (swelling of face)
- Febrile neutropenia (fever with reduced white blood cells)
- Plantar erythema (soles of the feet)
- Platelet count decreased
20-29:
- Back pain
- Bone marrow failure
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Dizziness
- Drug eruption (adverse drug reaction of the skin)
- Febrile neutropenia (fever with reduced white blood cells)
- Headache (pain in head)
- Hypoaesthesia (reduced sense of touch or sensation)
- Neoplasm progression (growth of tumour)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
30-39:
- Anticonvulsant drug level below therapeutic
- Blood bilirubin increased
- Clonus (series of involuntary, rhythmic, muscular contractions and relaxations)
- Fall
- Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
- Muscle spasms (muscle contraction)
40-49:
- Microangiopathy (disease of the capillaries (very small blood vessels), in which the capillary walls become so thick and weak that they bleed, leak protein)
- Febrile neutropenia (fever with reduced white blood cells)
50-59:
- Asthenia (weakness)
- Atelectasis (partial or complete collapse of the lung)
- Bacteria stool identified
- Clostridial infection (infectious conditions by clostridium bacteria)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Dyspnoea (difficult or laboured respiration)
- Febrile neutropenia (fever with reduced white blood cells)
- Lung neoplasm (tumour of lung)
60+:
- Pneumonia
- Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
- Pericarditis (inflammation of the pericardium)
- Respiratory distress (difficulty in breathing)
- Neutropenia (an abnormally low number of neutrophils)
- Renal failure (kidney dysfunction)
- Vomiting
- Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
- Acute myocardial infarction (acute heart attack)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
What are the existing conditions these people have? *
- High Blood Pressure: 7 people, 22.58%
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 7 people, 22.58%
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 6 people, 19.35%
- Respiratory Tract Infection: 5 people, 16.13%
- Bone Marrow Conditioning Regimen: 5 people, 16.13%
- Haematological Malignancy (cancer that affect blood, bone marrow, and lymph nodes): 5 people, 16.13%
- Multiple Myeloma (cancer of the plasma cells): 4 people, 12.90%
- Acute Lymphocytic Leukaemia Recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent): 3 people, 9.68%
- B Precursor Type Acute Leukaemia (lymphoid cancer): 3 people, 9.68%
- Febrile Neutropenia (fever with reduced white blood cells): 3 people, 9.68%
* Approximation only. Some reports may have incomplete information.
Do you take Augmentin and Fludarabine phosphate?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Augmentin (42,620 reports)
- Fludarabine phosphate (12,840 reports)
Browse all drug interactions of Augmentin and Fludarabine phosphate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Augmentin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Fludarabine phosphate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Augmentin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Fludarabine phosphate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium and fludarabine phosphate (the active ingredients of Augmentin and Fludarabine phosphate, respectively), and Augmentin and Fludarabine phosphate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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