Augmentin and Maxalt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Augmentin (amoxicillin; clavulanate potassium) and Maxalt (rizatriptan benzoate). Common drug interactions include dyspnoea among females and autoimmune arthritis among males.

The phase IV clinical study analyzes what interactions people have when they take Augmentin and Maxalt. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Augmentin?

Augmentin has active ingredients of amoxicillin; clavulanate potassium. It is often used in sinusitis. eHealthMe is studying from 42,620 Augmentin users. Check the latest studies of Augmentin.

What is Maxalt?

Maxalt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 12,754 Maxalt users. Check the latest studies of Maxalt.



On Jul, 20, 2026

93 people who take Augmentin and Maxalt together, and have interactions are studied.

Augmentin and Maxalt drug interactions.

What are the common drug interactions of Augmentin and Maxalt, by gender? *:

female:

  1. Dyspnoea (difficult or laboured respiration)
  2. Eyelid ptosis (falling of the upper or lower eyelid)
  3. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  4. General physical health deterioration (weak health status)
  5. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  6. Hospitalisation
  7. Hypercoagulation (increased tendency for clotting of the blood)
  8. Hyperventilation
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  10. Infusion site extravasation (flow of (blood or lymph) from infusion site)

male:

  1. Autoimmune arthritis (joint inflammation)
  2. Tendonitis (a condition that causes pain and swelling of tendons)
  3. Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
  4. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  5. Hydrocele
  6. Hydrocephalus (water on the brain)
  7. Hydronephrosis (water inside the kidney)
  8. Knee deformity (functional disability of knee)
  9. Lordosis (outward curve of the back bone)
  10. Mitral valve incompetence (inefficient heart valve)

What are the common drug interactions of Augmentin and Maxalt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Nausea (feeling of having an urge to vomit)
  2. Encephalopathy (functioning of the brain is affected by some agent or condition)
  3. Hepatic failure (liver failure)
  4. Hepatitis (inflammation of the liver)
  5. Hepatotoxicity (chemical-driven liver damage)
  6. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  7. Liver transplant
  8. Pruritus (severe itching of the skin)
  9. Aggression
  10. Agitation (state of anxiety or nervous excitement)

20-29:

  1. Nasal septum deviation (deviated nasal septum)
  2. Cholecystitis chronic (long lasting infection of gallbladder)
  3. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  4. Drug hypersensitivity
  5. Fall
  6. Gastric disorder (disease of stomach)
  7. Injury
  8. Limb injury
  9. Ovarian cyst (fluid filled sac of the ovary)
  10. Petit mal epilepsy (absence seizure)

30-39:

  1. Anxiety
  2. Nausea (feeling of having an urge to vomit)
  3. Depression
  4. Pain
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  7. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  8. Headache (pain in head)
  9. Pulmonary embolism (blockage of the main artery of the lung)
  10. Cervical spinal stenosis (narrowing of the spinal canal in the neck)

40-49:

  1. Blood urine present
  2. Calcium deficiency (lack of calcium)
  3. Cerebral infarction (less blood supply to brain resulting tissue damage)
  4. Decreased appetite
  5. Depression
  6. Dry skin
  7. Dyspnoea (difficult or laboured respiration)
  8. Eructation (release of gas from the digestive tract)
  9. Fatigue (feeling of tiredness)
  10. Gastritis (inflammation of stomach)

50-59:

  1. Arthropathy
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Depression
  4. Gastric disorder (disease of stomach)
  5. Thrombosis (formation of a blood clot inside a blood vessel)
  6. Atelectasis (partial or complete collapse of the lung)
  7. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  8. Chest pain
  9. Headache (pain in head)
  10. Insomnia (sleeplessness)

60+:

  1. Autoimmune arthritis (joint inflammation)
  2. Pneumonia
  3. Cerebral ventricle dilatation (enlargement of ventricle of brain)
  4. Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
  5. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  6. Hydrocele
  7. Hydrocephalus (water on the brain)
  8. Hydronephrosis (water inside the kidney)
  9. Knee deformity (functional disability of knee)
  10. Lordosis (outward curve of the back bone)

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 21 people, 22.58%
  2. Pain: 19 people, 20.43%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 18 people, 19.35%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 13 people, 13.98%
  5. High Blood Pressure: 9 people, 9.68%
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints): 9 people, 9.68%
  7. Nausea (feeling of having an urge to vomit): 7 people, 7.53%
  8. Joint Pain: 7 people, 7.53%
  9. Muscle Spasms (muscle contraction): 6 people, 6.45%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Augmentin and Maxalt?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Augmentin and Maxalt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Augmentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Maxalt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Augmentin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Maxalt and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amoxicillin; clavulanate potassium and rizatriptan benzoate (the active ingredients of Augmentin and Maxalt, respectively), and Augmentin and Maxalt (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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