Avandia and Rocephin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avandia (rosiglitazone maleate) and Rocephin (ceftriaxone sodium). Common drug interactions include hypoaesthesia among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Avandia and Rocephin. It is created by eHealthMe based on reports of 84 people who take the same drugs from the FDA, and is updated regularly.

What is Avandia?

Avandia has active ingredients of rosiglitazone maleate. It is often used in diabetes. eHealthMe is studying from 142,155 Avandia users. Check the latest studies of Avandia.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.

On Jul, 18, 2026

84 people who take Avandia and Rocephin together, and have interactions are studied.

What are the common drug interactions of Avandia and Rocephin, by gender? *:

female:

Hypoaesthesia (reduced sense of touch or sensation)
Sinusitis (inflammation of sinus)
Oedema peripheral (superficial swelling)
Cardiac failure congestive
Fatigue (feeling of tiredness)
Osteopenia (a condition where bone mineral density is lower than normal)
Sepsis (a severe blood infection that can lead to organ failure and death)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteoporosis (bones weak and more likely to break)

male:

Anaemia (lack of blood)
Back pain
Oedema peripheral (superficial swelling)
Renal failure acute (rapid kidney dysfunction)
Thrombocytopenia (decrease of platelets in blood)
Injury
Osteonecrosis of jaw (death of bone of jaw)
Hypertension (high blood pressure)
Asthenia (weakness)
Dizziness

What are the common drug interactions of Avandia and Rocephin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Acute pulmonary oedema (sudden deposit of fluid in the lung))
Cardiac failure congestive
Coronary arterial stent insertion
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)

20-29:

n/a

30-39:

Hypoaesthesia (reduced sense of touch or sensation)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Thermohypoaesthesia (a reduced sense of touch or sensation, or a partial loss of sensitivity to sensory stimuli heat)
Pain

40-49:

Anxiety
Back pain
Hypertension (high blood pressure)
Pain
Acidosis (build-up of carbon dioxide in the blood)
Anaemia (lack of blood)
Arthralgia (joint pain)
Asthenia (weakness)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)

50-59:

Pain
Sinusitis (inflammation of sinus)
Tricuspid valve incompetence (inefficient heart valve)
Abdominal pain
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
Anaemia (lack of blood)
Appendicitis (inflammation of the appendix)
Aptyalism (deficiency or absence of saliva)
Asthma
Bone disorder

60+:

Dyspnoea (difficult or laboured respiration)
Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Arthralgia (joint pain)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Hyperlipidaemia (presence of excess lipids in the blood)

What are the existing conditions these people have? *

Thrombocytopenia (decrease of platelets in blood): 10 people, 11.90%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 10 people, 11.90%
Osteoporosis (bones weak and more likely to break): 10 people, 11.90%
High Blood Pressure: 8 people, 9.52%
Pain: 7 people, 8.33%
Constipation: 7 people, 8.33%
Cellulitis (infection under the skin): 7 people, 8.33%
Bone Disorder: 7 people, 8.33%
Stress And Anxiety: 6 people, 7.14%
Multiple Myeloma (cancer of the plasma cells): 6 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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