Avastin and Premarin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avastin (bevacizumab) and Premarin (estrogens, conjugated). Common drug interactions include back pain among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Avastin and Premarin. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.

What is Avastin?

Avastin has active ingredients of bevacizumab. It is often used in high blood cholesterol. eHealthMe is studying from 76,365 Avastin users. Check the latest studies of Avastin.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

82 people who take Avastin and Premarin together, and have interactions are studied.

What are the common drug interactions of Avastin and Premarin, by gender? *:

female:

Back pain
Headache (pain in head)
Pruritus (severe itching of the skin)
Chest pain
Feeling hot
Vision blurred
Abdominal pain
Blood pressure increased
Drug intolerance (drug sensitivity)
Dysuria (painful or difficult urination)

male:

Pain
Death
Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Back pain
Bone disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac murmur functional (heart sound due to physiological condition outside the heart)
Chest pain
Chondropathy (disease of the cartilage)

What are the common drug interactions of Avastin and Premarin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Decreased appetite
Diarrhoea
Dyspepsia (indigestion)
Eye pain
Pruritus (severe itching of the skin)
Thrombocytopenia (decrease of platelets in blood)
Weight decreased
Dysgeusia (disorder of the sense of taste)

40-49:

Blood pressure increased
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Heart rate increased
Infusion related reaction
Nasopharyngitis (inflammation of the nasopharynx)
Peripheral swelling
Platelet count decreased
Protein urine present
Enterovesical fistula
Anxiety

50-59:

Death
Pain
Back pain
Dysphagia (a condition in which swallowing is difficult or painful)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Metastases to lung (cancer spreads to lung)
Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)

60+:

Visual acuity reduced (reduced clearness of vision)
Macular oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken)
Febrile neutropenia (fever with reduced white blood cells)
Posterior capsule opacification
Pyrexia (fever)
Urinary tract infection
Vision blurred
Visual impairment
Vitreous floaters (spots before the eyes)
Arthralgia (joint pain)

What are the existing conditions these people have? *

Colon Cancer: 11 people, 13.41%
Nausea (feeling of having an urge to vomit): 8 people, 9.76%
Lung Neoplasm Malignant (cancer tumour of lung): 7 people, 8.54%
Macular Degeneration (painless eye condition that leads to the gradual loss of central vision): 6 people, 7.32%
Lung Cancer - Non-Small Cell (lung cancer): 6 people, 7.32%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 6.10%
High Blood Pressure: 5 people, 6.10%

* Approximation only. Some reports may have incomplete information.

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