Avinza and Elavil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Avinza (morphine sulfate) and Elavil (amitriptyline hydrochloride). Common drug interactions include meningioma among females and anger among males.

The phase IV clinical study analyzes what interactions people have when they take Avinza and Elavil. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Avinza?

Avinza has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 1,728 Avinza users. Check the latest studies of Avinza.

What is Elavil?

Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 20,724 Elavil users. Check the latest studies of Elavil.

On Jul, 20, 2026

35 people who take Avinza and Elavil together, and have interactions are studied.

What are the common drug interactions of Avinza and Elavil, by gender? *:

female:

Meningioma (a diverse set of tumours arising from the meninges)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Metastases to bone (cancer spreads to bone)
Metastases to lung (cancer spreads to lung)
Metastatic neoplasm (spreadable cancer tumour)
Muscular weakness (muscle weakness)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteomyelitis (infection of bone)
Osteopenia (a condition where bone mineral density is lower than normal)
Pelvic abscess

male:

Anger
Anxiety
Depressed mood
Dizziness
Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dysuria (painful or difficult urination)
Ear infection
Emotional disorder
Emotional distress

What are the common drug interactions of Avinza and Elavil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Injury
Pulmonary embolism (blockage of the main artery of the lung)
Thrombosis (formation of a blood clot inside a blood vessel)

40-49:

Emotional disorder
Emotional distress
Feeling of despair
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
General physical health deterioration (weak health status)
Hostility
Hyperhidrosis (abnormally increased sweating)
Impaired driving ability
Impaired reasoning
Injury

50-59:

n/a

60+:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Mass
Cardiac failure congestive
Carotid artery stenosis (narrowing of carotid artery)
Cellulitis (infection under the skin)
Cerebral atrophy (decrement in size of brain)
Chronic inflammatory demyelinating polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord)
Colostomy
Contusion (a type of hematoma of tissue in which capillaries)
Deafness

What are the existing conditions these people have? *

Insomnia (sleeplessness): 10 people, 28.57%
Sleep Disorder: 9 people, 25.71%
Stress And Anxiety: 6 people, 17.14%
Urinary Tract Infection: 5 people, 14.29%
Neuralgia (pain in one or more nerves): 5 people, 14.29%
Muscle Aches (muscle pain): 5 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 14.29%
Fluid Retention (an abnormal accumulation of fluid in the blood): 5 people, 14.29%
Blood Calcium Decreased: 5 people, 14.29%
Osteoporosis (bones weak and more likely to break): 4 people, 11.43%

* Approximation only. Some reports may have incomplete information.

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