Azithromycin and Zantac 75 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azithromycin (azithromycin) and Zantac 75 (ranitidine hydrochloride). Common drug interactions include renal injury among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Azithromycin and Zantac 75. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.

What is Zantac 75?

Zantac 75 has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 3,796 Zantac 75 users. Check the latest studies of Zantac 75.

On Jul, 18, 2026

48 people who take Azithromycin and Zantac 75 together, and have interactions are studied.

Azithromycin and Zantac 75 drug interactions.

What are the common drug interactions of Azithromycin and Zantac 75, by gender? *:

female:

Renal injury (kidney injury)
Constipation
Essential hypertension (primary hypertension)
Death
Renal cell carcinoma (a kidney cancer)
Chronic kidney disease
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Hyperkalaemia (damage to or disease of the kidney)
Hypertension (high blood pressure)

male:

Chronic kidney disease
Death
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

What are the common drug interactions of Azithromycin and Zantac 75, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)

40-49:

Chronic kidney disease
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Hyperkalaemia (damage to or disease of the kidney)
Renal failure (kidney dysfunction)

50-59:

Chronic kidney disease
Hypertension (high blood pressure)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Death
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Renal cell carcinoma (a kidney cancer)
Renal injury (kidney injury)

What are the existing conditions these people have? *

Pain: 39 people, 81.25%
Infection: 35 people, 72.92%
High Blood Pressure: 29 people, 60.42%
High Blood Cholesterol: 25 people, 52.08%
Blood Pressure Abnormal: 10 people, 20.83%
Depression: 9 people, 18.75%
Muscle Spasms (muscle contraction): 8 people, 16.67%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 8 people, 16.67%
Indigestion: 8 people, 16.67%
Headache (pain in head): 8 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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