Azopt and Sodium bicarbonate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Azopt (brinzolamide) and Sodium bicarbonate (sodium bicarbonate). Common drug interactions include seizure among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Azopt and Sodium bicarbonate. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Azopt?

Azopt has active ingredients of brinzolamide. It is often used in glaucoma. eHealthMe is studying from 8,058 Azopt users. Check the latest studies of Azopt.

What is Sodium bicarbonate?

Sodium bicarbonate has active ingredients of sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 27,283 Sodium bicarbonate users. Check the latest studies of Sodium bicarbonate.

On Jul, 21, 2026

33 people who take Azopt and Sodium bicarbonate together, and have interactions are studied.

Azopt and Sodium bicarbonate drug interactions.

What are the common drug interactions of Azopt and Sodium Bicarbonate, by gender? *:

female:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Anticonvulsant drug level decreased
Cataract (clouding of the lens inside the eye)
Confusional state
Memory impairment
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Syncope (loss of consciousness with an inability to maintain postural tone)
Urinary tract infection
Blindness
Arthralgia (joint pain)

male:

Fall
Upper limb fracture
Muscle spasms (muscle contraction)
Obstruction
Peripheral swelling
Renal failure (kidney dysfunction)
Bronchopneumopathy
Haemoglobin decreased
Lung disorder (lung disease)
Abdominal pain upper

What are the common drug interactions of Azopt and Sodium Bicarbonate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Arthralgia (joint pain)
Cardiac failure acute
Decreased appetite
Erythema nodosum (skin inflammation that results in reddish, painful, tender lumps most commonly located in the front of the legs below)
Gastric ulcer (stomach ulcer)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Nasal ulcer (ulcer of nose)
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)

30-39:

Dehydration (dryness resulting from the removal of water)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

40-49:

n/a

50-59:

Abdominal pain upper
Anaemia (lack of blood)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Diarrhoea
Disease progression
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Insomnia (sleeplessness)
Malignant pleural effusion (a condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue lining of lung)
Multiple myeloma (cancer of the plasma cells)

60+:

Fall
Upper limb fracture
Mood altered (changes in mood)
Muscle spasms (muscle contraction)
Obstruction
Peripheral swelling
Bronchopneumopathy
Haemoglobin decreased
Lung disorder (lung disease)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 27.27%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 6 people, 18.18%
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract): 6 people, 18.18%
High Blood Cholesterol: 4 people, 12.12%
High Blood Pressure: 4 people, 12.12%
Rickets (softening of bones): 4 people, 12.12%
Renal Disorder (kidney disease): 4 people, 12.12%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 4 people, 12.12%
Infection: 4 people, 12.12%
Diabetes: 4 people, 12.12%

* Approximation only. Some reports may have incomplete information.

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