Baclofen and Axid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Baclofen (baclofen) and Axid (nizatidine). Common drug interactions include pruritus among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Baclofen and Axid. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Baclofen?

Baclofen has active ingredients of baclofen. It is often used in muscle spasms. eHealthMe is studying from 108,662 Baclofen users. Check the latest studies of Baclofen.

What is Axid?

Axid has active ingredients of nizatidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 2,980 Axid users. Check the latest studies of Axid.

On Jul, 14, 2026

57 people who take Baclofen and Axid together, and have interactions are studied.

What are the common drug interactions of Baclofen and Axid, by gender? *:

female:

Pruritus (severe itching of the skin)
Pulmonary oedema (fluid accumulation in the lungs)
Pulse absent
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Finger deformity (a deformed position of the finger)
Hilar lymphadenopathy (disease of the lymph nodes due to infection)
Hyperventilation
Peripheral occlusive disease (narrowing of blood vessels that restricts blood flow)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthralgia (joint pain)

male:

Chronic kidney disease
Abdominal pain
Asthenia (weakness)
Burning sensation
Cellulitis (infection under the skin)
Confusional state
Constipation
Crying
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression

What are the common drug interactions of Baclofen and Axid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Impaired gastric emptying

10-19:

Urate urine increased

20-29:

Cardiac disorder
Migraine (headache)
Type 1 diabetes mellitus
Cardiac failure congestive
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Joint injury
Thrombosis (formation of a blood clot inside a blood vessel)
Viral cardiomyopathy (weakness in the muscle of the heart due to viral infection)

30-39:

Anxiety
Depression
Fall
Headache (pain in head)
Abdominal pain
Affective disorder (mental disorder)
Asthenia (weakness)
Burning sensation
Cellulitis (infection under the skin)
Confusional state

40-49:

Arterial bruit (heart murmur)
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
Asthma
Body temperature increased
Cardiac disorder
Cardiac murmur (an heart sound in valve abnormality)
Catheter site infection (infection at the site of insertion)
Central nervous system stimulation
Contusion (a type of hematoma of tissue in which capillaries)
Exfoliative rash (scaly red generalized skin rash)

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Death
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Renal injury (kidney injury)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Hypotension (abnormally low blood pressure)
Muscle disorder (muscle disease)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Nocturia (the need to get up in the night to urinate)
Oedema lower limb (fluid collection in tissue of lower leg)
Paralysis
Peripheral swelling

What are the existing conditions these people have? *

Pain: 26 people, 45.61%
High Blood Pressure: 12 people, 21.05%
Depression: 8 people, 14.04%
Infection: 8 people, 14.04%
Stress And Anxiety: 7 people, 12.28%
Insomnia (sleeplessness): 7 people, 12.28%
Cough: 7 people, 12.28%
Chest Pain: 6 people, 10.53%
Joint Pain: 6 people, 10.53%
Multiple Allergies (allergy to multiple agents): 5 people, 8.77%

* Approximation only. Some reports may have incomplete information.

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