Bactrim ds and Tecfidera drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bactrim ds (sulfamethoxazole; trimethoprim) and Tecfidera (dimethyl fumarate). Common drug interactions include generalised erythema among females and hyponatraemia among males.

The phase IV clinical study analyzes what interactions people have when they take Bactrim ds and Tecfidera. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Bactrim ds?

Bactrim ds has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 17,027 Bactrim ds users. Check the latest studies of Bactrim ds.

What is Tecfidera?

Tecfidera has active ingredients of dimethyl fumarate. It is often used in multiple sclerosis. eHealthMe is studying from 129,627 Tecfidera users. Check the latest studies of Tecfidera.

On Jul, 16, 2026

52 people who take Bactrim ds and Tecfidera together, and have interactions are studied.

Bactrim ds and Tecfidera drug interactions.

What are the common drug interactions of Bactrim Ds and Tecfidera, by gender? *:

female:

Generalised erythema (redness of the skin all over the body)
Hip fracture
Immune thrombocytopenic purpura (destruction of blood platelets due to the presence of antiplatelet auto antibodies)
Fall
Hypoaesthesia (reduced sense of touch or sensation)
Decreased appetite
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Heparin-induced thrombocytopenia
Hot flush (sudden feelings of heat)

male:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Paraplegia (paralysis of the legs and lower body)
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Death
Depressed mood
Fatigue (feeling of tiredness)
Hearing impaired
Hyperhidrosis (abnormally increased sweating)
Malaise (a feeling of general discomfort or uneasiness)
Tinnitus (a ringing in the ears)

What are the common drug interactions of Bactrim Ds and Tecfidera, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Atelectasis (partial or complete collapse of the lung)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Pneumonia
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Confusional state
Constipation
Decreased appetite
Incontinence (lack of moderation or self-control)
Tremor (trembling or shaking movements in one or more parts of your body)

40-49:

Abdominal pain
Biliary dilatation
Dizziness
Fatigue (feeling of tiredness)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Palpitations (feelings or sensations that your heart is pounding or racing)
Red blood cell count decreased
White blood cell count decreased

50-59:

Fatigue (feeling of tiredness)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Blood urine present
Depression
Dysarthria (speech disorder)
Dysgraphia (impaired ability to learn to write)
Gait disturbance
Hypoaesthesia (reduced sense of touch or sensation)
Micturition urgency (urgency to pass the urine)
Muscular weakness (muscle weakness)

60+:

Fall
Decreased appetite
Nocardiosis (an infectious disease affecting either the lungs or whole body)
Pulmonary embolism (blockage of the main artery of the lung)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Brain neoplasm (tumour of brain)
Lung disorder (lung disease)
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Cns ventriculitis (inflammation of the ventricles in the brain)

What are the existing conditions these people have? *

Gait Disturbance: 6 people, 11.54%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

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