Bactrim and Lemtrada drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bactrim (sulfamethoxazole; trimethoprim) and Lemtrada (alemtuzumab). Common drug interactions include albumin urine present among females and oropharyngeal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Bactrim and Lemtrada. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

What is Lemtrada?

Lemtrada has active ingredients of alemtuzumab. eHealthMe is studying from 8,317 Lemtrada users. Check the latest studies of Lemtrada.



On Jul, 26, 2026

42 people who take Bactrim and Lemtrada together, and have interactions are studied.

Bactrim and Lemtrada drug interactions.

What are the common drug interactions of Bactrim and Lemtrada, by gender? *:

female:

  1. Albumin urine present
  2. Alpha 1 globulin decreased
  3. Arthralgia (joint pain)
  4. Aspartate aminotransferase decreased
  5. Blood alkaline phosphatase decreased
  6. Blood bicarbonate decreased
  7. Blood calcium decreased
  8. Blood creatine phosphokinase decreased
  9. Blood phosphorus increased
  10. Blood uric acid increased

male:

  1. Oropharyngeal pain
  2. Pyrexia (fever)
  3. Fatigue (feeling of tiredness)
  4. Asthenia (weakness)
  5. Gait disturbance
  6. Insomnia (sleeplessness)
  7. Nasopharyngitis (inflammation of the nasopharynx)
  8. Platelet count decreased
  9. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  10. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the common drug interactions of Bactrim and Lemtrada, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Influenza like illness
  2. Lymphopenia (an abnormally low level of lymphocytes in the blood)
  3. Monocytopenia (a deficiency of monocytes)
  4. Bone marrow failure
  5. Dyspnoea (difficult or laboured respiration)
  6. Headache (pain in head)
  7. Hypersomnia (excessive daytime sleepiness (eds))
  8. Leukopenia (less number of white blood cells in blood)
  9. Melanocytic naevus (a type of lesion that contains nevus cells (a type of melanocyte))
  10. Mobility decreased (ability to move is reduced)

30-39:

  1. Chest discomfort
  2. Headache (pain in head)
  3. Dyspnoea (difficult or laboured respiration)
  4. Heart rate increased
  5. Nausea (feeling of having an urge to vomit)
  6. Somnolence (a state of near-sleep, a strong desire for sleep)
  7. Feeling cold
  8. Feeling hot
  9. Flushing (the warm, red condition of human skin)
  10. Hypotension (abnormally low blood pressure)

40-49:

  1. Lymphocyte percentage decreased
  2. Neutrophil percentage increased
  3. Urinary sediment present
  4. White blood cells urine positive
  5. Albumin urine present
  6. Alpha 1 globulin decreased
  7. Aspartate aminotransferase decreased
  8. Blood alkaline phosphatase decreased
  9. Blood bicarbonate decreased
  10. Blood calcium decreased

50-59:

  1. Contusion (a type of hematoma of tissue in which capillaries)
  2. Gingival bleeding (bleeding gums)
  3. Immune thrombocytopenic purpura (destruction of blood platelets due to the presence of antiplatelet auto antibodies)
  4. Oropharyngeal pain
  5. Petechiae (a small red or purple spot caused by bleeding into the skin)
  6. Rash macular (small, flat red spots)
  7. Skin haemorrhage (bleeding into skin)
  8. Thrombosis (formation of a blood clot inside a blood vessel)
  9. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  10. Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

  1. Gait disturbance
  2. Insomnia (sleeplessness)
  3. Deafness unilateral
  4. Decreased appetite
  5. Diarrhoea
  6. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  7. Dysphagia (a condition in which swallowing is difficult or painful)
  8. Dyspnoea (difficult or laboured respiration)
  9. Ear infection
  10. Fall

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 32 people, 76.19%
  2. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 8 people, 19.05%
  3. Vitamin D Decreased: 4 people, 9.52%
  4. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 4 people, 9.52%
  5. Muscle Spasms (muscle contraction): 4 people, 9.52%
  6. Interstitial Nephritis (inflammation of the kidney): 4 people, 9.52%
  7. Hypersensitivity: 4 people, 9.52%
  8. High Blood Cholesterol: 4 people, 9.52%
  9. Folate Deficiency (lack of folic acid): 4 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bactrim and Lemtrada:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bactrim:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lemtrada:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bactrim and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lemtrada and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on sulfamethoxazole; trimethoprim and alemtuzumab (the active ingredients of Bactrim and Lemtrada, respectively), and Bactrim and Lemtrada (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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