Benadryl and Flovent hfa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Benadryl (diphenhydramine hydrochloride) and Flovent hfa (fluticasone propionate). Common drug interactions include nasopharyngitis among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Benadryl and Flovent hfa. It is created by eHealthMe based on reports of 234 people who take the same drugs from the FDA, and is updated regularly.

What is Benadryl?

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. eHealthMe is studying from 104,955 Benadryl users. Check the latest studies of Benadryl.

What is Flovent hfa?

Flovent hfa has active ingredients of fluticasone propionate. It is often used in asthma. eHealthMe is studying from 7,457 Flovent hfa users. Check the latest studies of Flovent hfa.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 24, 2026

234 people who take Benadryl and Flovent hfa together, and have interactions are studied.

Benadryl and Flovent hfa drug interactions.

What are the common drug interactions of Benadryl and Flovent hfa, by gender? *

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What are the common drug interactions of Benadryl and Flovent hfa, by age (0-1 to 60+)? *

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What are the existing conditions these people have? *

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* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Benadryl and Flovent hfa:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Benadryl:

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Browse all side effects of Flovent hfa:

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Browse all interactions between Benadryl and drugs from A to Z:

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Browse all interactions between Flovent hfa and drugs from A to Z:

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Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride and fluticasone propionate (the active ingredients of Benadryl and Flovent hfa, respectively), and Benadryl and Flovent hfa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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