Benadryl and Terconazole drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Benadryl (diphenhydramine hydrochloride) and Terconazole (terconazole). Common drug interactions include urinary tract infection among females.
The phase IV clinical study analyzes what interactions people have when they take Benadryl and Terconazole. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.
What is Benadryl?
Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. eHealthMe is studying from 104,954 Benadryl users. Check the latest studies of Benadryl.
What is Terconazole?
Terconazole has active ingredients of terconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 1,004 Terconazole users. Check the latest studies of Terconazole.
56 people who take Benadryl and Terconazole together, and have interactions are studied.

What are the common drug interactions of Benadryl and Terconazole, by gender? *:
female:
- Urinary tract infection
- Upper respiratory tract infection
- Nausea (feeling of having an urge to vomit)
- Anaemia (lack of blood)
- Conjunctivitis viral (infection of conjunctiva by virus)
- Dyspnoea (difficult or laboured respiration)
- Gastritis (inflammation of stomach)
- Herpes zoster
- Pain
- Urticaria (rash of round, red welts on the skin that itch intensely)
male:
n/a
What are the common drug interactions of Benadryl and Terconazole, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Anaemia (lack of blood)
- Asthenia (weakness)
- Conjunctivitis viral (infection of conjunctiva by virus)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Nausea (feeling of having an urge to vomit)
- Urinary tract infection
- Vomiting
- Food poisoning (poison in food)
- Gastritis (inflammation of stomach)
- Herpes zoster
30-39:
- Haemorrhage (bleeding)
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Cholecystitis chronic (long lasting infection of gallbladder)
- Chronic kidney disease
- Contusion (a type of hematoma of tissue in which capillaries)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Diarrhoea
- Fungal infection
- Injection site pain
- Pulmonary embolism (blockage of the main artery of the lung)
40-49:
- Sinusitis (inflammation of sinus)
- Upper respiratory tract infection
- Urinary tract infection
- Kidney infection
- Bacterial infection
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
- Ear infection
- Fatigue (feeling of tiredness)
- Influenza
50-59:
- Lymphocyte count increased
- Malaise (a feeling of general discomfort or uneasiness)
- Mania (a state of abnormally elevated or irritable mood)
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Mitral valve incompetence (inefficient heart valve)
- Mobility decreased (ability to move is reduced)
- Monocyte count decreased
- Muscle spasms (muscle contraction)
- Muscular weakness (muscle weakness)
- Nausea (feeling of having an urge to vomit)
60+:
- Chronic kidney disease
- Dysphagia (a condition in which swallowing is difficult or painful)
- Influenza
- Nephrogenic anaemia (anaemia due to kidney disease)
- Pyrexia (fever)
- Renal failure (kidney dysfunction)
- Ventricular fibrillation (abnormally irregular heart rhythm)
- Vomiting
- Abdominal pain upper
- Agitation (state of anxiety or nervous excitement)
What are the existing conditions these people have? *
- Immunodeficiency Common Variable: 12 people, 21.43%
- Hypersensitivity: 10 people, 17.86%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 16.07%
- Primary Immunodeficiency Syndrome: 8 people, 14.29%
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 8 people, 14.29%
- Pain: 7 people, 12.50%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 12.50%
- Fungal Infection: 6 people, 10.71%
- Infection: 6 people, 10.71%
- Rickets (softening of bones): 6 people, 10.71%
* Approximation only. Some reports may have incomplete information.
Do you take Benadryl and Terconazole?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Benadryl (104,954 reports)
- Terconazole (1,004 reports)
Browse all drug interactions of Benadryl and Terconazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Benadryl:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Terconazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Benadryl and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Terconazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on diphenhydramine hydrochloride and terconazole (the active ingredients of Benadryl and Terconazole, respectively), and Benadryl and Terconazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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