Benadryl and Timentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Benadryl (diphenhydramine hydrochloride) and Timentin (clavulanate potassium; ticarcillin disodium). Common drug interactions include bronchitis among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Benadryl and Timentin. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Benadryl?

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. eHealthMe is studying from 104,956 Benadryl users. Check the latest studies of Benadryl.

What is Timentin?

Timentin has active ingredients of clavulanate potassium; ticarcillin disodium. eHealthMe is studying from 624 Timentin users. Check the latest studies of Timentin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

40 people who take Benadryl and Timentin together, and have interactions are studied.

Benadryl and Timentin drug interactions.

What are the common drug interactions of Benadryl and Timentin, by gender? *:

female:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiomegaly (increased size of heart than normal)
Chills (felling of cold)
Colitis (inflammation of colon)
Constipation
Diarrhoea
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Emotional distress
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Empyema (collection of pus in a cavity in the body)

male:

Constipation
Staphylococcal infection (an infection with staphylococcus bacteria)
Nausea (feeling of having an urge to vomit)
Pleural effusion (water on the lungs)
Sepsis (a severe blood infection that can lead to organ failure and death)
Vomiting
Abscess (pus)
Cardiac failure congestive
Cytomegalovirus infection
Dementia (madness)

What are the common drug interactions of Benadryl and Timentin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)

10-19:

Pancreatitis (inflammation of pancreas)

20-29:

Abscess jaw (tooth abscess or root abscess)
Anaemia of chronic disease
Anxiety
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Back pain

30-39:

Chest pain
Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)
Hypersensitivity
Pain

40-49:

Constipation
Lymphocele (a collection of lymphatic fluid within the body not bordered by epithelial lining)
Wound dehiscence (a surgical incision reopens either internally or externally)
Abdominal pain
Abscess (pus)
Cytomegalovirus infection
Faecal impaction
Fall
Pyrexia (fever)
Staphylococcal infection (an infection with staphylococcus bacteria)

50-59:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Granuloma (a small area of inflammation due to tissue injury)
Hyperplasia (enlargement of an organ or tissue)
Kaposi's sarcoma (a tumour caused by human herpes virus)
Lymphadenopathy (disease or enlargement of lymph nodes)
Lymphoma (cancer that begins in immune system cells)
Nephritis interstitial (a kidney condition characterized by swelling in between the kidney tubules)

60+:

Neutropenia (an abnormally low number of neutrophils)
Anxiety
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Dyspnoea (difficult or laboured respiration)
Emotional distress
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Empyema (collection of pus in a cavity in the body)
Exostosis (formation of new bone on the surface of a bone)
Fatigue (feeling of tiredness)
Granuloma (a small area of inflammation due to tissue injury)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 2 people, 5.00%
Insomnia (sleeplessness): 2 people, 5.00%
Analgesic Effect: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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