Benicar and Ceftriaxone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Benicar (olmesartan medoxomil) and Ceftriaxone (ceftriaxone sodium). Common drug interactions include metabolic acidosis among females and pneumonia among males.
The phase IV clinical study analyzes what interactions people have when they take Benicar and Ceftriaxone. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.
What is Benicar?
Benicar has active ingredients of olmesartan medoxomil. It is often used in high blood pressure. eHealthMe is studying from 36,002 Benicar users. Check the latest studies of Benicar.
What is Ceftriaxone?
Ceftriaxone has active ingredients of ceftriaxone sodium. It is often used in typhoid fever. eHealthMe is studying from 40,991 Ceftriaxone users. Check the latest studies of Ceftriaxone.
22 people who take Benicar and Ceftriaxone together, and have interactions are studied.

What are the common drug interactions of Benicar and Ceftriaxone, by gender? *:
female:
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
- Muscle spasms (muscle contraction)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Oedema peripheral (superficial swelling)
- Pharyngeal mass
- Pruritus (severe itching of the skin)
- Renal failure chronic (long lasting kidney dysfunction)
- Renal injury (kidney injury)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Yawning (simultaneous inhalation of air and stretching of the eardrums, followed by exhalation of breath)
male:
- Pneumonia
- Blood creatinine increased
- Renal failure acute (rapid kidney dysfunction)
- Thrombocytopenia (decrease of platelets in blood)
- Haemorrhage (bleeding)
- Rash
- Renal haemorrhage (bleeding from kidney)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Abdominal pain upper
- Asthenia (weakness)
What are the common drug interactions of Benicar and Ceftriaxone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Back pain
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Agitation (state of anxiety or nervous excitement)
- Blood creatine phosphokinase increased
- Blood creatinine increased
- Clonus (series of involuntary, rhythmic, muscular contractions and relaxations)
- Confusional state
- Dyskinesia (abnormality or impairment of voluntary movement)
60+:
- Pneumonia
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Orthopnoea (shortness of breath (dyspnea) when lying down)
- Renal failure acute (rapid kidney dysfunction)
- Thrombocytopenia (decrease of platelets in blood)
- Rash
- Nausea (feeling of having an urge to vomit)
- Abdominal pain upper
- Asthenia (weakness)
- Chronic kidney disease
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 40.91%
- Depression: 6 people, 27.27%
- High Blood Cholesterol: 5 people, 22.73%
- Infection: 5 people, 22.73%
- Pain: 5 people, 22.73%
- Bacterial Infection: 4 people, 18.18%
- Migraine (headache): 3 people, 13.64%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 13.64%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 13.64%
- Weight Loss: 2 people, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Benicar and Ceftriaxone?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Benicar (36,002 reports)
- Ceftriaxone (40,991 reports)
Browse all drug interactions of Benicar and Ceftriaxone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Benicar:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ceftriaxone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Benicar and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ceftriaxone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on olmesartan medoxomil and ceftriaxone sodium (the active ingredients of Benicar and Ceftriaxone, respectively), and Benicar and Ceftriaxone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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