Betaseron and Reglan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Betaseron (interferon beta-1b) and Reglan (metoclopramide hydrochloride). Common drug interactions include injection site erythema among females and infection among males.
The phase IV clinical study analyzes what interactions people have when they take Betaseron and Reglan. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.
What is Betaseron?
Betaseron has active ingredients of interferon beta-1b. It is often used in multiple sclerosis. eHealthMe is studying from 26,886 Betaseron users. Check the latest studies of Betaseron.
What is Reglan?
Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.
43 people who take Betaseron and Reglan together, and have interactions are studied.

What are the common drug interactions of Betaseron and Reglan, by gender? *:
female:
- Injection site erythema (redness at injection site)
- Injection site inflammation
- Injection site reaction
- Insomnia (sleeplessness)
- Lip injury
- Loss of consciousness
- Malaise (a feeling of general discomfort or uneasiness)
- Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
- Nasopharyngitis (inflammation of the nasopharynx)
- Fatigue (feeling of tiredness)
male:
- Infection
- Injection site cellulitis (injection site inflammation)
- Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
- Metastases to liver (cancer spreads to liver)
- Muscle spasms (muscle contraction)
- Optic neuritis (optic nerve inflammation)
- Renal cyst (kidney cyst)
- Syringomyelia (cavity forms within the spinal cord)
- Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
What are the common drug interactions of Betaseron and Reglan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Dizziness
- Dyspnoea (difficult or laboured respiration)
- Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
- Nervous system disorder (a general class of medical conditions affecting the nervous system)
- Cardiomegaly (increased size of heart than normal)
- Chest discomfort
30-39:
- Anger
- Burning sensation
- Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
- Cough
- Depression
- Dyspnoea (difficult or laboured respiration)
- Impulsive behaviour
- Intervertebral disc protrusion (spinal disc protrusion)
- Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
- Mood swings (an extreme or rapid change in mood)
40-49:
- Abdominal distension
- Abdominal pain
- Device dislocation
- Dysmenorrhoea (painful menstruation)
- Fatigue (feeling of tiredness)
- Lymphocyte count decreased
- Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
- Migraine (headache)
- Uterine haemorrhage (uterine bleeding)
- Back pain
50-59:
- Adverse drug reaction
- Arthropathy
- Asthma
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Dizziness
- Dyspepsia (indigestion)
- Endometrial cancer
- Haematoma (collection of blood outside the blood vessels)
- Hypertension (high blood pressure)
60+:
- Infection
- Injection site cellulitis (injection site inflammation)
- Central nervous system necrosis (destruction of central nervous system)
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Immune system disorder
- Malaise (a feeling of general discomfort or uneasiness)
- Memory impairment
- Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot)
- Epistaxis (bleed from the nose)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
What are the existing conditions these people have? *
- Depression: 6 people, 13.95%
- Pain: 3 people, 6.98%
- Migraine Without Aura (headache without neurological problems): 3 people, 6.98%
- Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 3 people, 6.98%
- Fatigue (feeling of tiredness): 3 people, 6.98%
* Approximation only. Some reports may have incomplete information.
Do you take Betaseron and Reglan?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Betaseron and Reglan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Betaseron:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Reglan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Betaseron and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Reglan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on interferon beta-1b and metoclopramide hydrochloride (the active ingredients of Betaseron and Reglan, respectively), and Betaseron and Reglan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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