Bextra and Magnesium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bextra (valdecoxib) and Magnesium (magnesium). Common drug interactions include arthralgia among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Bextra and Magnesium. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Bextra?

Bextra has active ingredients of valdecoxib. It is often used in pain. eHealthMe is studying from 20,994 Bextra users. Check the latest studies of Bextra.

What is Magnesium?

Magnesium has active ingredients of magnesium. It is often used in constipation. eHealthMe is studying from 121,144 Magnesium users. Check the latest studies of Magnesium.



On Jul, 18, 2026

56 people who take Bextra and Magnesium together, and have interactions are studied.

Bextra and Magnesium drug interactions.

What are the common drug interactions of Bextra and Magnesium, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Bone disorder
  3. Intervertebral disc protrusion (spinal disc protrusion)
  4. Chest pain
  5. Urinary retention (the inability to completely or partially empty the bladder)
  6. Decreased appetite
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Joint effusion (presence of extra fluid in joint covering)
  9. Mouth ulceration (mouth ulcers)
  10. Neuritis (inflammation of nerve)

male:

  1. Anxiety
  2. Injury
  3. Bacteraemia (presence of bacteria in the blood)
  4. Bone disorder
  5. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  6. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  7. Deformity (disfigurement)
  8. Febrile neutropenia (fever with reduced white blood cells)
  9. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  10. Hypercholesterolaemia (high levels of cholesterol in the blood)

What are the common drug interactions of Bextra and Magnesium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
  2. Adenoma benign (non-cancerous tumour -secreting)
  3. Adnexa uteri cyst (ovarian cysts)
  4. Allergic sinusitis
  5. Anxiety
  6. Aortic arteriosclerosis (hardening of the aortic arteries)
  7. Aortic calcification (aortic calcification sign of heart valve disease)
  8. Aortic valve sclerosis (narrowing of the aortic valve)
  9. Arthralgia (joint pain)
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints)

30-39:

n/a

40-49:

  1. Dyspnoea (difficult or laboured respiration)
  2. Hyperlipidaemia (presence of excess lipids in the blood)
  3. Abdominal distension
  4. Abdominal pain
  5. Anaemia (lack of blood)
  6. Anxiety
  7. Bacteraemia (presence of bacteria in the blood)
  8. Bone disorder
  9. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  10. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

50-59:

  1. Cardiac failure congestive
  2. Hepatic cyst
  3. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  4. Spinal osteoarthritis (joint cartilage loss in spine)
  5. Abdominal pain
  6. Acquired oesophageal web (structural abnormalities in the oesophagus)
  7. Anxiety
  8. Bone disorder
  9. Breast cancer recurrent
  10. Cellulitis (infection under the skin)

60+:

  1. Bone disorder
  2. Dizziness
  3. Osteosclerosis (an elevation in bone density)
  4. Rash
  5. Rib fracture
  6. Urinary retention (the inability to completely or partially empty the bladder)
  7. Actinomycosis (infection that causes sores, or abscesses)
  8. Alopecia (absence of hair from areas of the body)
  9. Asthenia (weakness)
  10. Atelectasis (partial or complete collapse of the lung)

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 15 people, 26.79%
  2. High Blood Pressure: 11 people, 19.64%
  3. Multiple Myeloma (cancer of the plasma cells): 9 people, 16.07%
  4. Hypersensitivity: 9 people, 16.07%
  5. Depression: 8 people, 14.29%
  6. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 7 people, 12.50%
  7. Menopause (end of monthly cycles in women): 7 people, 12.50%
  8. Back Pain: 7 people, 12.50%
  9. Insomnia (sleeplessness): 7 people, 12.50%
  10. Sinus Disorder (disease of sinus): 7 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Bextra and Magnesium?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bextra and Magnesium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bextra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Magnesium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bextra and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Magnesium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on valdecoxib and magnesium (the active ingredients of Bextra and Magnesium, respectively), and Bextra and Magnesium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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