Bicalutamide and Capecitabine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Bicalutamide (bicalutamide) and Capecitabine (capecitabine). Common drug interactions include malignant neoplasm progression among females and disease progression among males.
The phase IV clinical study analyzes what interactions people have when they take Bicalutamide and Capecitabine. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.
What is Bicalutamide?
Bicalutamide has active ingredients of bicalutamide. It is often used in prostate cancer. eHealthMe is studying from 9,930 Bicalutamide users. Check the latest studies of Bicalutamide.
What is Capecitabine?
Capecitabine has active ingredients of capecitabine. eHealthMe is studying from 59,495 Capecitabine users. Check the latest studies of Capecitabine.
24 people who take Bicalutamide and Capecitabine together, and have interactions are studied.

What are the common drug interactions of Bicalutamide and Capecitabine, by gender? *:
female:
- Malignant neoplasm progression (cancer tumour came back)
- Metastases to liver (cancer spreads to liver)
- Metastases to lung (cancer spreads to lung)
- Disease progression
- Metastases to lymph nodes (cancer spreads to lymph node)
- Metastases to skin (cancer spreads to skin)
- Abdominal discomfort
- Alopecia (absence of hair from areas of the body)
- Asthenia (weakness)
- Decreased appetite
male:
- Disease progression
- Fatigue (feeling of tiredness)
- Drug intolerance (drug sensitivity)
- Extramammary paget's disease (cancer of an epithelium that originates in glandular tissue)
- Hypercholesterolaemia (high levels of cholesterol in the blood)
- Metastases to central nervous system (cancer spreads to central nervous system)
- Metastases to eye (cancer spreads to eye)
- Rectal cancer (cancer of rectum)
- Thrombocytopenia (decrease of platelets in blood)
- Walking disability
What are the common drug interactions of Bicalutamide and Capecitabine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Malignant neoplasm progression (cancer tumour came back)
- Metastases to liver (cancer spreads to liver)
- Metastases to lung (cancer spreads to lung)
40-49:
- Cardiotoxicity (damage to the heart muscle)
- Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
50-59:
- Disease progression
- Fatigue (feeling of tiredness)
- Febrile neutropenia (fever with reduced white blood cells)
- Anaemia (lack of blood)
- Asthenia (weakness)
- Depressed mood
- Mobility decreased (ability to move is reduced)
- Drug intolerance (drug sensitivity)
- Extramammary paget's disease (cancer of an epithelium that originates in glandular tissue)
- Walking disability
60+:
- Hypertension (high blood pressure)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Chills (felling of cold)
- Decreased appetite
- Eye irritation
- Fall
- Oral mucosal blistering (mouth ulcer)
- Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
- Palpitations (feelings or sensations that your heart is pounding or racing)
What are the existing conditions these people have? *
- Extramammary Paget's Disease (cancer of an epithelium that originates in glandular tissue): 6 people, 25.00%
- Neoplasm Malignant (cancer tumour): 2 people, 8.33%
- Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 2 people, 8.33%
- Breast Cancer Stage Iv: 2 people, 8.33%
- Breast Cancer: 2 people, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Bicalutamide and Capecitabine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Bicalutamide (9,930 reports)
- Capecitabine (59,495 reports)
Browse all drug interactions of Bicalutamide and Capecitabine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Bicalutamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Capecitabine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Bicalutamide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Capecitabine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .
- Pinto HP, Bhat RM, Shet D, Dandekeri S, "Compound mucocutaneous adverse effects of oral capecitabine in a patient", Indian dermatology online journal, 2014 Jan .
- Kang SM, Baek JY, Hwangbo B, Kim HY, Lee GK, Lee HS, "A case of capecitabine-induced sarcoidosis", Tuberculosis and respiratory diseases, 2012 Mar .
- Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .
- Pinto HP, Bhat RM, Shet D, Dandekeri S, "Compound mucocutaneous adverse effects of oral capecitabine in a patient", Indian dermatology online journal, 2014 Jan .
- Kang SM, Baek JY, Hwangbo B, Kim HY, Lee GK, Lee HS, "A case of capecitabine-induced sarcoidosis", Tuberculosis and respiratory diseases, 2012 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on bicalutamide and capecitabine (the active ingredients of Bicalutamide and Capecitabine, respectively), and Bicalutamide and Capecitabine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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