Bicalutamide and Zantac drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Bicalutamide (bicalutamide) and Zantac (ranitidine hydrochloride). Common drug interactions include asthenia among males.
The phase IV clinical study analyzes what interactions people have when they take Bicalutamide and Zantac. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.
What is Bicalutamide?
Bicalutamide has active ingredients of bicalutamide. It is often used in prostate cancer. eHealthMe is studying from 9,930 Bicalutamide users. Check the latest studies of Bicalutamide.
What is Zantac?
Zantac has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 434,161 Zantac users. Check the latest studies of Zantac.
34 people who take Bicalutamide and Zantac together, and have interactions are studied.

What are the common drug interactions of Bicalutamide and Zantac, by gender? *:
female:
n/a
male:
- Asthenia (weakness)
- Fatigue (feeling of tiredness)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Back pain
- Blood pressure increased
- Breath sounds
- Cardiac failure
- Constipation
- Cough
- Dizziness
What are the common drug interactions of Bicalutamide and Zantac, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Asthenia (weakness)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Blood pressure increased
- Breath sounds
- Cough
- Fatigue (feeling of tiredness)
- Heart rate decreased
- Heart rate increased
- Heart rate irregular
- Lower respiratory tract infection
60+:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Fatigue (feeling of tiredness)
- Hypocalcaemia (levels of calcium in blood serum are abnormally low)
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Proteinuria (presence of protein in the urine)
- Pyrexia (fever)
- Vomiting
- Renal injury (kidney injury)
What are the existing conditions these people have? *
- Pain: 5 people, 14.71%
- Kidney Stones: 4 people, 11.76%
- Gastric Ulcer (stomach ulcer): 3 people, 8.82%
- Enlarged Prostate: 3 people, 8.82%
- Bladder Spasm: 3 people, 8.82%
- Blood Pressure Abnormal: 3 people, 8.82%
- Colon Cancer Metastatic (cancer of colon spreads to other part of body): 3 people, 8.82%
- Constipation: 3 people, 8.82%
- Cerebral Infarction (less blood supply to brain resulting tissue damage): 2 people, 5.88%
- Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 2 people, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Bicalutamide and Zantac?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Bicalutamide (9,930 reports)
- Zantac (434,161 reports)
Browse all drug interactions of Bicalutamide and Zantac:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Bicalutamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zantac:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Bicalutamide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zantac and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .
- Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on bicalutamide and ranitidine hydrochloride (the active ingredients of Bicalutamide and Zantac, respectively), and Bicalutamide and Zantac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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