Bifido and Tacrolimus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bifido (bifidobacteria) and Tacrolimus (tacrolimus). Common drug interactions include compression fracture among females and gingivitis ulcerative among males.

The phase IV clinical study analyzes what interactions people have when they take Bifido and Tacrolimus. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Bifido?

Bifido has active ingredients of bifidobacteria. eHealthMe is studying from 5,030 Bifido users. Check the latest studies of Bifido.

What is Tacrolimus?

Tacrolimus has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 116,160 Tacrolimus users. Check the latest studies of Tacrolimus.

On Jul, 26, 2026

62 people who take Bifido and Tacrolimus together, and have interactions are studied.

Bifido and Tacrolimus drug interactions.

What are the common drug interactions of Bifido and Tacrolimus, by gender? *:

female:

Compression fracture (fracture due to pressure caused by injury)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Constipation
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Gastric dilatation (a twisted stomach)
Immunosuppression
Infusion related reaction
Neuralgia (pain in one or more nerves)
Pain
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)

male:

Gingivitis ulcerative (infection of gums with ulcers)
Dyspnoea (difficult or laboured respiration)
Megacolon (a very dilated colon)
Pathogen resistance
Pseudomembranous colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon)
Sepsis (a severe blood infection that can lead to organ failure and death)
Wound dehiscence (a surgical incision reopens either internally or externally)
Depressed level of consciousness
Immunosuppressant drug level decreased
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Bifido and Tacrolimus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Eyelid irritation
Injection site pain
Urinary tract infection
Pruritus (severe itching of the skin)
Rash

10-19:

Gingivitis ulcerative (infection of gums with ulcers)
Burning sensation
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Pruritus (severe itching of the skin)
Therapeutic response decreased (less preventive response)

20-29:

Drug clearance decreased
Drug clearance increased
Drug level decreased
Heart transplant rejection
Alanine aminotransferase increased
Amino acid level increased
Aspartate aminotransferase increased
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Cholecystitis (infection of gallbladder)
Decreased appetite

30-39:

Diarrhoea
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Clostridium test positive
Constipation
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dyspnoea (difficult or laboured respiration)
Enterococcus test positive
Haematochezia (passage of stools containing blood)
Haemorrhage (bleeding)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)

40-49:

Anaemia (lack of blood)
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
Sleep disorder
Infection
Conjunctivitis (pink eye)
Eye pruritus (eye itching)
Impaired driving ability
Photophobia (extreme sensitivity to light)
Pruritus (severe itching of the skin)
Scleral discolouration (change colour of sclera)

50-59:

Loss of consciousness
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Pneumonia
Pruritus (severe itching of the skin)
Therapeutic response decreased (less preventive response)
Sepsis (a severe blood infection that can lead to organ failure and death)
Depressed level of consciousness
Immunosuppressant drug level decreased
Nausea (feeling of having an urge to vomit)
Septic shock (shock due to blood infection)

60+:

Pyelonephritis (inflammation of kidney caused by bacteria)
Anaemia (lack of blood)
Back pain
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Initial insomnia (feeling of inadequate or poor-quality sleep)
Injection site bruising
Injection site pruritus (severe itching at injection site)
Injection site swelling
Oral herpes (viral infection of mouth)

What are the existing conditions these people have? *

Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 14 people, 22.58%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 13 people, 20.97%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 9.68%
Immunodeficiency Common Variable: 5 people, 8.06%
Adverse Event: 5 people, 8.06%
Insomnia (sleeplessness): 4 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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