Brethine and Ibuprofen drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Brethine (terbutaline sulfate) and Ibuprofen (ibuprofen). Common drug interactions include emotional disorder among females and anxiety among males.
The phase IV clinical study analyzes what interactions people have when they take Brethine and Ibuprofen. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.
What is Brethine?
Brethine has active ingredients of terbutaline sulfate. eHealthMe is studying from 480 Brethine users. Check the latest studies of Brethine.
What is Ibuprofen?
Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.
30 people who take Brethine and Ibuprofen together, and have interactions are studied.

What are the common drug interactions of Brethine and Ibuprofen, by gender? *:
female:
- Emotional disorder
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
- Oligohydramnios (a condition in pregnancy characterized by a deficiency of amniotic fluid)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anxiety
- Drug dependence
- Anger
- Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
- Chronic kidney disease
- Exacerbation of anxiety (increase in the severity of anxiety)
male:
- Anxiety
- Drug exposure during pregnancy
- Brain neoplasm (tumour of brain)
- Chylothorax (collection of lymph fluid around the lung)
- Contusion (a type of hematoma of tissue in which capillaries)
- Epistaxis (bleed from the nose)
- Muscle spasms (muscle contraction)
- Nausea (feeling of having an urge to vomit)
- Poisoning
- Pruritus (severe itching of the skin)
What are the common drug interactions of Brethine and Ibuprofen, by age (0-1 to 60+)? *:
0-1:
- Foetal growth restriction (poor growth of a baby while in the mother's womb during pregnancy)
- Pulmonary hypertension (increase in blood pressure in the lung artery)
- Right ventricular hypertrophy (right ventricular enlargement)
2-9:
n/a
10-19:
n/a
20-29:
- Emotional disorder
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
- Oligohydramnios (a condition in pregnancy characterized by a deficiency of amniotic fluid)
30-39:
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anxiety
- Drug dependence
- Anger
- Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
- Exacerbation of anxiety (increase in the severity of anxiety)
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Mania (a state of abnormally elevated or irritable mood)
- Neuropathy peripheral (surface nerve damage)
- Renal failure (kidney dysfunction)
40-49:
n/a
50-59:
- Chronic kidney disease
60+:
- Abdominal pain upper
- Constipation
- Jaundice neonatal (yellowing of skin in neonate)
- Mitral valve incompetence (inefficient heart valve)
- Muscle spasms (muscle contraction)
- Nausea (feeling of having an urge to vomit)
- Poisoning
- Prothrombin time shortened
- Pruritus (severe itching of the skin)
- Pulmonary hypertension (increase in blood pressure in the lung artery)
What are the existing conditions these people have? *
- Stress And Anxiety: 17 people, 56.67%
- Depression: 14 people, 46.67%
- Ill-Defined Disorder: 9 people, 30.00%
- Type 2 Diabetes: 7 people, 23.33%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 7 people, 23.33%
- Migraine (headache): 7 people, 23.33%
- Blood Disorder: 6 people, 20.00%
- Nausea (feeling of having an urge to vomit): 6 people, 20.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 16.67%
- High Blood Pressure: 5 people, 16.67%
* Approximation only. Some reports may have incomplete information.
Do you take Brethine and Ibuprofen?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Brethine and Ibuprofen:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Brethine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ibuprofen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Brethine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ibuprofen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on terbutaline sulfate and ibuprofen (the active ingredients of Brethine and Ibuprofen, respectively), and Brethine and Ibuprofen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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