Bumetanide and Prolensa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Bumetanide (bumetanide) and Prolensa (bromfenac sodium). Common drug interactions include chronic kidney disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Bumetanide and Prolensa. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Bumetanide?

Bumetanide has active ingredients of bumetanide. It is often used in fluid retention. eHealthMe is studying from 20,532 Bumetanide users. Check the latest studies of Bumetanide.

What is Prolensa?

Prolensa has active ingredients of bromfenac sodium. eHealthMe is studying from 1,170 Prolensa users. Check the latest studies of Prolensa.



On Jul, 17, 2026

12 people who take Bumetanide and Prolensa together, and have interactions are studied.

Bumetanide and Prolensa drug interactions.

What are the common drug interactions of Bumetanide and Prolensa, by gender? *:

female:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Gastric ulcer (stomach ulcer)
  4. Suicidal ideation
  5. Renal injury (kidney injury)
  6. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

male:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
  4. Renal disorder (kidney disease)
  5. Renal failure (kidney dysfunction)
  6. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  7. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  8. Dry eye (lack of adequate tears)
  9. Nausea (feeling of having an urge to vomit)
  10. Pleural effusion (water on the lungs)

What are the common drug interactions of Bumetanide and Prolensa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  2. Renal injury (kidney injury)
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Renal disorder (kidney disease)
  5. Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
  6. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  7. Chronic kidney disease
  8. Renal failure (kidney dysfunction)
  9. Gastric ulcer (stomach ulcer)
  10. Suicidal ideation

60+:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  5. Renal disorder (kidney disease)
  6. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 66.67%
  2. Pain: 7 people, 58.33%
  3. Stress And Anxiety: 7 people, 58.33%
  4. Depression: 7 people, 58.33%
  5. Gastric Ulcer (stomach ulcer): 6 people, 50.00%
  6. High Blood Cholesterol: 6 people, 50.00%
  7. High Blood Pressure: 6 people, 50.00%
  8. Stable Angina (a constant chest pain): 6 people, 50.00%
  9. Diabetes: 6 people, 50.00%
  10. Inflammation: 6 people, 50.00%

* Approximation only. Some reports may have incomplete information.

Do you take Bumetanide and Prolensa?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Bumetanide and Prolensa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Bumetanide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prolensa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bumetanide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prolensa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bumetanide and bromfenac sodium (the active ingredients of Bumetanide and Prolensa, respectively), and Bumetanide and Prolensa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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