Buscopan and Morphine sulfate drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Buscopan (hyoscine butylbromide) and Morphine sulfate (morphine sulfate). Common drug interactions include bone lesion among females and bronchitis among males.
The phase IV clinical study analyzes what interactions people have when they take Buscopan and Morphine sulfate. It is created by eHealthMe based on reports of 97 people who take the same drugs from the FDA, and is updated regularly.
What is Buscopan?
Buscopan has active ingredients of hyoscine butylbromide. eHealthMe is studying from 4,828 Buscopan users. Check the latest studies of Buscopan.
What is Morphine sulfate?
Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 87,261 Morphine sulfate users. Check the latest studies of Morphine sulfate.
97 people who take Buscopan and Morphine sulfate together, and have interactions are studied.

What are the common drug interactions of Buscopan and Morphine Sulfate, by gender? *:
female:
- Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
- Dehydration (dryness resulting from the removal of water)
- Insomnia (sleeplessness)
- Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
- Oxygen saturation decreased
- Vision blurred
- Abortion spontaneous (naturally occurring miscarriage)
- Acarodermatitis (skin inflammation caused by mites (acarids))
- Adverse event
- Anxiety
male:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Colitis (inflammation of colon)
- Pyrexia (fever)
- Weight decreased
- Soft tissue infection
- Anxiety
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Blood pressure increased
- Drug hypersensitivity
- Fall
What are the common drug interactions of Buscopan and Morphine Sulfate, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Diarrhoea
- Febrile neutropenia (fever with reduced white blood cells)
- Haemoglobin decreased
- Hypophagia (reduced food intake)
- Pleural effusion (water on the lungs)
- Respiratory distress (difficulty in breathing)
- Vomiting
- Weight decreased
10-19:
- Blood pressure decreased
- Face oedema (swelling of face)
- Flushing (the warm, red condition of human skin)
- Headache (pain in head)
- Mydriasis (a dilation of the pupil)
- Oxygen saturation decreased
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Loss of consciousness
- Vision blurred
20-29:
- Dizziness
- Vertigo
- Asthenia (weakness)
- Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
- Colitis ulcerative (inflammation of colon with ulcer)
- Delirium (wild excitement)
- General physical health deterioration (weak health status)
- Pneumonia
- Post procedural complication
- Pyrexia (fever)
30-39:
- Abortion spontaneous (naturally occurring miscarriage)
- Adverse event
- Aphonia (inability to produce voice)
- Kidney infection
- Malaise (a feeling of general discomfort or uneasiness)
- Maternal exposure during pregnancy (use of substance during pregnancy)
- Nephrolithiasis (calculi in the kidneys)
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
- Surgery
- Urinary tract infection
40-49:
- Pancreatic carcinoma (pancreatic cancer)
- Pancreatic neoplasm (pancreatic tumour)
- Pharyngeal abscess
- Pharyngitis (inflammation of the pharynx, causing a sore throat)
- Pituitary tumour
- Post procedural infection
- Protein urine present
- Pyrexia (fever)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Skin infection
50-59:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Colitis (inflammation of colon)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Dehydration (dryness resulting from the removal of water)
- Quadriplegia (a four limb paralysis)
- Constipation
- Diarrhoea
- Skin infection
- Urinary tract infection
- Abscess (pus)
60+:
- Diarrhoea
- Drug ineffective
- Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
- Hypokalaemia (low potassium)
- Insomnia (sleeplessness)
- Oxygen saturation decreased
- Dehydration (dryness resulting from the removal of water)
- Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
- Neoplasm progression (growth of tumour)
- Neuropathy peripheral (surface nerve damage)
What are the existing conditions these people have? *
- Abdominal Pain Upper: 27 people, 27.84%
- Nausea (feeling of having an urge to vomit): 13 people, 13.40%
- Constipation: 10 people, 10.31%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 7.22%
- Stress And Anxiety: 6 people, 6.19%
- High Blood Pressure: 6 people, 6.19%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 6.19%
* Approximation only. Some reports may have incomplete information.
Do you take Buscopan and Morphine sulfate?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Buscopan (4,828 reports)
- Morphine sulfate (87,261 reports)
Browse all drug interactions of Buscopan and Morphine sulfate:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Buscopan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Morphine sulfate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Buscopan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Morphine sulfate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
- Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on hyoscine butylbromide and morphine sulfate (the active ingredients of Buscopan and Morphine sulfate, respectively), and Buscopan and Morphine sulfate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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