Buspar and Afinitor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Buspar (buspirone hydrochloride) and Afinitor (everolimus). Common drug interactions include menstrual disorder among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Buspar and Afinitor. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Buspar?

Buspar has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 20,463 Buspar users. Check the latest studies of Buspar.

What is Afinitor?

Afinitor has active ingredients of everolimus. It is often used in breast cancer metastatic. eHealthMe is studying from 41,680 Afinitor users. Check the latest studies of Afinitor.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

29 people who take Buspar and Afinitor together, and have interactions are studied.

What are the common drug interactions of Buspar and Afinitor, by gender? *:

female:

Menstrual disorder (disease of menstrual cycle)
Muscular weakness (muscle weakness)
Night sweats (sweating in night)
Peripheral swelling
Pneumonia
Renal impairment (severely reduced kidney function)
Tinea pedis (a contagious skin infection caused by the ringworm fungus)
Tonsillar hypertrophy (enlargement of the tonsils)
Malaise (a feeling of general discomfort or uneasiness)
Blood pressure increased

male:

Weight decreased
Arthralgia (joint pain)
Dental caries
Peripheral swelling
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Ear pain
Asthenia (weakness)
Eating disorder
Generalised oedema (swelling all over the body)
Hypersomnia (excessive daytime sleepiness (eds))

What are the common drug interactions of Buspar and Afinitor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Vomiting
Cheilitis (infection of lips)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Ear pain
Menstrual disorder (disease of menstrual cycle)
Pain
Peripheral swelling
Pneumonia
Renal disorder (kidney disease)
Tinea pedis (a contagious skin infection caused by the ringworm fungus)

20-29:

Muscle atrophy (a decrease in the mass of the muscle)

30-39:

Weight decreased
Arthralgia (joint pain)
Body mass index increased
Drug level decreased
Drug level increased
Oedema (fluid collection in tissue)
Hypertension (high blood pressure)
Weight increased
Back pain
Cardiomegaly (increased size of heart than normal)

40-49:

n/a

50-59:

Blood potassium increased
Dyspnoea (difficult or laboured respiration)
Malaise (a feeling of general discomfort or uneasiness)
Nasopharyngitis (inflammation of the nasopharynx)
Pancreatitis (inflammation of pancreas)
Blood phosphorus decreased
Cough
Fall
Glossodynia (a burning or painful sensation in the tongue)
Haemoglobin decreased

60+:

Disease progression
Drug ineffective
Hepatic mass

What are the existing conditions these people have? *

Angiomyolipoma (most common benign tumour of the kidney): 12 people, 41.38%
Brain Neoplasm Benign (non-cancerous tumour of brain): 6 people, 20.69%
Tuberous Sclerosis (a rare genetic disease that causes benign tumours to grow in the brain and other organs): 5 people, 17.24%
Renal Pain (kidney pain): 4 people, 13.79%
Astrocytoma, Low Grade (low grade tumour of the brain that originate in a particular kind of glial-cells): 3 people, 10.34%
Constipation: 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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