Buspirone hcl and Prolia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Buspirone hcl (buspirone hydrochloride) and Prolia (denosumab). Common drug interactions include irritable bowel syndrome among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Buspirone hcl and Prolia. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Buspirone hcl?

Buspirone hcl has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,821 Buspirone hcl users. Check the latest studies of Buspirone hcl.

What is Prolia?

Prolia has active ingredients of denosumab. It is often used in osteoporosis. eHealthMe is studying from 151,388 Prolia users. Check the latest studies of Prolia.

On Jul, 12, 2026

48 people who take Buspirone hcl and Prolia together, and have interactions are studied.

Buspirone hcl and Prolia drug interactions.

What are the common drug interactions of Buspirone Hcl and Prolia, by gender? *:

female:

Irritable bowel syndrome
Joint swelling
Lethargy (tiredness)
Migraine (headache)
Muscle contracture (a permanent shortening of a muscle)
Myoclonic epilepsy (type of epilepsy with quick little jerks of the arms, shoulder, or occasionally the legs)
Oedema peripheral (superficial swelling)
Overdose
Pain
Paranasal sinus hypersecretion

male:

Arthralgia (joint pain)
Asthenia (weakness)
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Gait disturbance
Hospitalisation
Middle ear effusion (fluid in middle ear)
Muscle spasticity (tight or stiff muscles and an inability to control those muscles)
Muscular weakness (muscle weakness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the common drug interactions of Buspirone Hcl and Prolia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Procedural pain
Pyrexia (fever)
Road traffic accident
Upper limb fracture
Muscle spasms (muscle contraction)
Pancreatic carcinoma (pancreatic cancer)
Sinusitis (inflammation of sinus)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Hypoxia (low oxygen in tissues)
Nasopharyngitis (inflammation of the nasopharynx)

60+:

Fatigue (feeling of tiredness)
Fall
Sinusitis (inflammation of sinus)
Injection site pain
Seasonal allergy (allergic condition due to certain season)
Ankle fracture
Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Anaemia (lack of blood)
Arthritis (form of joint disorder that involves inflammation of one or more joints)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 9 people, 18.75%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 18.75%
B-Lymphocyte Abnormalities (abnormal population of b lymphocytes in the blood, bone marrow, or tissues): 6 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 12.50%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 10.42%
High Blood Pressure: 5 people, 10.42%
Thyroid Diseases: 4 people, 8.33%
Pain: 4 people, 8.33%
Drowsiness: 3 people, 6.25%
Ear Disorder: 3 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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