Viekira pak and Zyrtec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Viekira pak (dasabuvir sodium ; ombitasvir; paritaprevir; ritonavir) and Zyrtec (cetirizine hydrochloride). Common drug interactions include flatulence among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Viekira pak and Zyrtec. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.

What is Viekira pak?

Viekira pak has active ingredients of dasabuvir sodium ; ombitasvir; paritaprevir; ritonavir. eHealthMe is studying from 10,521 Viekira pak users. Check the latest studies of Viekira pak.

What is Zyrtec?

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 114,619 Zyrtec users. Check the latest studies of Zyrtec.



On Jul, 12, 2026

75 people who take Viekira pak and Zyrtec together, and have interactions are studied.

Viekira pak and Zyrtec drug interactions.

What are the common drug interactions of Viekira Pak and Zyrtec, by gender? *:

female:

  1. Flatulence (flatus expelled through the anus)
  2. Fluid intake reduced
  3. Gait disturbance
  4. Gallbladder disorder
  5. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  6. Generalised erythema (redness of the skin all over the body)
  7. Head discomfort
  8. Initial insomnia (feeling of inadequate or poor-quality sleep)
  9. Memory impairment
  10. Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)

male:

  1. Fatigue (feeling of tiredness)
  2. Headache (pain in head)
  3. Migraine (headache)
  4. Ocular icterus (presence of jaundice seen in the sclera of the eye)
  5. Pruritus (severe itching of the skin)
  6. Rash
  7. Pain
  8. Road traffic accident
  9. Abdominal pain upper
  10. Arthralgia (joint pain)

What are the common drug interactions of Viekira Pak and Zyrtec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Blood bilirubin increased
  2. Fatigue (feeling of tiredness)
  3. Foetal death (death of foetus)
  4. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  5. Nausea (feeling of having an urge to vomit)
  6. Ocular icterus (presence of jaundice seen in the sclera of the eye)
  7. Abortion spontaneous (naturally occurring miscarriage)
  8. Blood alkaline phosphatase increased

40-49:

  1. Abdominal distension
  2. Abdominal pain
  3. Abdominal pain upper
  4. Diarrhoea
  5. Nausea (feeling of having an urge to vomit)

50-59:

  1. Fatigue (feeling of tiredness)
  2. Insomnia (sleeplessness)
  3. Headache (pain in head)
  4. Nausea (feeling of having an urge to vomit)
  5. Pruritus (severe itching of the skin)
  6. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  7. Anaemia (lack of blood)
  8. Blood bilirubin increased
  9. Decreased appetite
  10. Migraine (headache)

60+:

  1. Fatigue (feeling of tiredness)
  2. Nausea (feeling of having an urge to vomit)
  3. Pruritus (severe itching of the skin)
  4. Blood glucose increased
  5. Blood potassium decreased
  6. Blood pressure increased
  7. Blood sodium decreased
  8. Blood urea increased
  9. Dry skin
  10. Erythema (redness of the skin)

What are the existing conditions these people have? *

  1. Hepatitis C: 66 people, 88.00%
  2. Hypersensitivity: 11 people, 14.67%
  3. Seasonal Allergy (allergic condition due to certain season): 5 people, 6.67%
  4. High Blood Pressure: 5 people, 6.67%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 6.67%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 5.33%

* Approximation only. Some reports may have incomplete information.

Do you take Viekira pak and Zyrtec?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Viekira pak and Zyrtec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Viekira pak:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zyrtec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Viekira pak and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zyrtec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on dasabuvir sodium ; ombitasvir; paritaprevir; ritonavir and cetirizine hydrochloride (the active ingredients of Viekira pak and Zyrtec, respectively), and Viekira pak and Zyrtec (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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