Calcium and Magnesium drug interactions - from FDA reports


Drug interactions are reported among people who take Calcium and Magnesium together. This study is created by eHealthMe based on reports of 6,714 people who take Calcium and Magnesium from FDA, and is updated regularly.

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On Dec, 27, 2018

6,714 people who take Calcium, Magnesium are studied.


Number of reports submitted per year:

Calcium and Magnesium drug interactions.

Most common drug interactions over time *:

1 - 6 months:
  1. Blood alkaline phosphatase increased
  2. Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
  3. Decreased appetite
  4. Drug ineffective
  5. Dyspepsia (indigestion)
  6. Dyspnoea (difficult or laboured respiration)
  7. Gamma-glutamyltransferase increased
  8. Gastroduodenal haemorrhage (bleeding from stomach or duodenum ulcer)
  9. General physical health deterioration (weak health status)
  10. Hepatomegaly (abnormal enlargement of the liver)
6 - 12 months:
  1. Weight increased
  2. Pain
  3. Androgen deficiency
  4. Brain cancer metastatic
  5. Death
  6. Diarrhoea
  7. Fatigue (feeling of tiredness)
  8. Hypersensitivity
  9. Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries))
  10. Incontinence (lack of moderation or self-control)
1 - 2 years:
  1. Gastroduodenal haemorrhage (bleeding from stomach or duodenum ulcer)
  2. Iron deficiency anaemia
  3. Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
  4. Bone density abnormal
  5. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
  6. Endometrial cancer
  7. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
  8. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  9. Neoplasm progression (growth of tumour)
  10. Night sweats (sweating in night)
2 - 5 years:
  1. Pneumonia
  2. Thrombosis (formation of a blood clot inside a blood vessel)
  3. Asthma
  4. Diarrhoea haemorrhagic (bloody diarrhoea)
  5. Ankle fracture
  6. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  7. Fall
  8. Gastroduodenal haemorrhage (bleeding from stomach or duodenum ulcer)
  9. Iron deficiency anaemia
  10. Pulmonary tuberculosis (lungs tuberculosis)
5 - 10 years:
  1. Diarrhoea
  2. Gastric disorder (disease of stomach)
  3. Nausea (feeling of having an urge to vomit)
  4. Oropharyngeal pain
  5. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
10+ years:
  1. Arteriovenous fistula
  2. Arteriovenous malformation
  3. Haemorrhoids (a swollen vein or group of veins in the region of the anus)
  4. Hypercalciuria (elevated calcium (ca+) level in the urine)
  5. Hyperkeratosis (thickening of the outer layer of the skin)
  6. Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)
  7. Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
  8. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  9. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  10. Nausea (feeling of having an urge to vomit)
not specified:
  1. Fatigue (feeling of tiredness)
  2. Nausea (feeling of having an urge to vomit)
  3. Diarrhoea
  4. Drug ineffective
  5. Headache (pain in head)
  6. Pain
  7. Arthralgia (joint pain)
  8. Dizziness
  9. Asthenia (weakness)
  10. Fall

Most common drug interactions by gender *:

female:
  1. Dizziness
  2. Pain in extremity
  3. Fall
  4. Dyspnoea (difficult or laboured respiration)
  5. Asthenia (weakness)
  6. Muscle spasms (muscle contraction)
  7. Insomnia (sleeplessness)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Vomiting
  10. Back pain
male:
  1. Fatigue (feeling of tiredness)
  2. Diarrhoea
  3. Pain
  4. Anaemia (lack of blood)
  5. Pain in extremity
  6. Blood glucose increased
  7. Weight decreased
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Back pain
  10. Headache (pain in head)

Most common drug interactions by age *:

0-1:
  1. Hypercalciuria (elevated calcium (ca+) level in the urine)
  2. Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)
  3. Nephrocalcinosis (a condition in which calcium levels in the kidneys are increased)
  4. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  5. Motor developmental delay (delayed walking and doing self movement)
  6. Premature baby
  7. Ventricular arrhythmia (problem with the rate or rhythm of the heartbeat)
  8. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  9. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  10. Abdominal pain upper
2-9:
  1. Depressed level of consciousness
  2. Electrolyte imbalance
  3. Renal failure (kidney dysfunction)
  4. Nephropathy toxic (damage to kidney due to toxins)
  5. Polyuria (production of too much dilute urine)
  6. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  7. Abdominal discomfort
  8. Adenovirus infection
  9. Anaemia (lack of blood)
  10. Anxiety
10-19:
  1. Drug ineffective
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Pain
  4. Chest pain
  5. Dyspepsia (indigestion)
  6. Fatigue (feeling of tiredness)
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Panic attack
  9. Thyroid disorder (thyroid diseases)
  10. Insomnia (sleeplessness)
20-29:
  1. Diarrhoea
  2. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  3. Drug level increased
  4. Chest pain
  5. Pyrexia (fever)
  6. Nausea (feeling of having an urge to vomit)
  7. Headache (pain in head)
  8. Feeling cold
  9. Dizziness
  10. Fatigue (feeling of tiredness)
30-39:
  1. Nausea (feeling of having an urge to vomit)
  2. Fatigue (feeling of tiredness)
  3. Pain in extremity
  4. Arthralgia (joint pain)
  5. Vomiting
  6. Haemoglobin decreased
  7. Urinary tract infection
  8. Muscular weakness (muscle weakness)
  9. Dizziness
  10. Muscle spasms (muscle contraction)
40-49:
  1. Nausea (feeling of having an urge to vomit)
  2. Fatigue (feeling of tiredness)
  3. Headache (pain in head)
  4. Blood glucose increased
  5. Dizziness
  6. Arthralgia (joint pain)
  7. Vomiting
  8. Anaemia (lack of blood)
  9. Pain
  10. Lymphocyte count decreased
50-59:
  1. Fatigue (feeling of tiredness)
  2. Nausea (feeling of having an urge to vomit)
  3. Diarrhoea
  4. Pain
  5. Headache (pain in head)
  6. Drug ineffective
  7. Arthralgia (joint pain)
  8. Dyspnoea (difficult or laboured respiration)
  9. Vomiting
  10. Insomnia (sleeplessness)
60+:
  1. Rash
  2. Insomnia (sleeplessness)
  3. Back pain
  4. Pruritus (severe itching of the skin)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Urinary tract infection
  7. Cough
  8. Vomiting
  9. Weight decreased
  10. Pneumonia

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study



Do you take Calcium and Magnesium?


You are not alone:




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Browse by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


Interactions between Calcium and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Interactions between Magnesium and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Browse all drug interactions of Calcium and Magnesium
a b c d e f g h i j k l m n o p q r s t u v w x y z

What would happen?

Predict new side effects and undetected conditions when you take Calcium and Magnesium (15,229 reports studied)

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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