Captopril and Flonase drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Captopril (captopril) and Flonase (fluticasone propionate). Common drug interactions include loss of consciousness among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Captopril and Flonase. It is created by eHealthMe based on reports of 81 people who take the same drugs from the FDA, and is updated regularly.

What is Captopril?

Captopril has active ingredients of captopril. It is often used in high blood pressure. eHealthMe is studying from 17,438 Captopril users. Check the latest studies of Captopril.

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.



On Jul, 10, 2026

81 people who take Captopril and Flonase together, and have interactions are studied.

Captopril and Flonase drug interactions.

What are the common drug interactions of Captopril and Flonase, by gender? *:

female:

  1. Loss of consciousness
  2. Atrioventricular block complete (heart block complete)
  3. Azotaemia (excess of urea or other nitrogenous compounds in the blood)
  4. Cardiomyopathy (weakening of the heart muscle)
  5. Concussion (short loss of normal brain function in response to a head injury)
  6. Facial bones fracture (bone fracture of face)
  7. Hyperglycaemia (high blood sugar)
  8. Hyperkalaemia (damage to or disease of the kidney)
  9. Hypoglycaemia (deficiency of glucose in the bloodstream)
  10. Hypovolaemia (a decreased volume of circulating blood in the body)

male:

  1. Headache (pain in head)
  2. Cardiac failure congestive
  3. Lymphadenopathy mediastinal (an enlargement of the lymph nodes in the part of the chest that separates the lungs)
  4. Malignant pleural effusion (a condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue lining of lung)
  5. Metastases to liver (cancer spreads to liver)
  6. Metastases to retroperitoneum (cancer spreads to retroperitonium)
  7. Neoplasm malignant (cancer tumour)
  8. Neoplasm progression (growth of tumour)
  9. Osteonecrosis (death of bone)
  10. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

What are the common drug interactions of Captopril and Flonase, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Cough
  2. Device related infection
  3. Fatigue (feeling of tiredness)
  4. Haematocrit decreased
  5. Hyperchlorhydria (gastric acid levels are higher in stomach)
  6. Increased bronchial secretion
  7. Lethargy (tiredness)
  8. Lip dry
  9. Lip exfoliation
  10. Lymphocyte percentage increased

10-19:

  1. Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)

20-29:

n/a

30-39:

n/a

40-49:

  1. Chronic kidney disease
  2. Osteonecrosis (death of bone)
  3. Anxiety
  4. Asthenia (weakness)
  5. Back pain
  6. Cardiac failure congestive
  7. Cardiac murmur (an heart sound in valve abnormality)
  8. Cardiomegaly (increased size of heart than normal)
  9. Cough
  10. Dizziness

50-59:

  1. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  2. Cellulitis (infection under the skin)
  3. Drug ineffective
  4. Fatigue (feeling of tiredness)
  5. Pulmonary oedema (fluid accumulation in the lungs)
  6. Respiratory distress (difficulty in breathing)
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Aggression
  9. Anaphylactic reaction (serious allergic reaction)
  10. Anxiety

60+:

  1. Cardiac failure congestive
  2. Urinary tract infection
  3. Decreased appetite
  4. Facial bones fracture (bone fracture of face)
  5. Fall
  6. Hyperglycaemia (high blood sugar)
  7. Hyperkalaemia (damage to or disease of the kidney)
  8. Hypoglycaemia (deficiency of glucose in the bloodstream)
  9. Hypotension (abnormally low blood pressure)
  10. Hypovolaemia (a decreased volume of circulating blood in the body)

What are the existing conditions these people have? *

  1. Pain: 12 people, 14.81%
  2. Stress And Anxiety: 9 people, 11.11%
  3. Hypersensitivity: 7 people, 8.64%
  4. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 7.41%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 7.41%
  6. Diabetes: 6 people, 7.41%
  7. Chest Pain: 6 people, 7.41%
  8. Psoriasis (immune-mediated disease that affects the skin): 5 people, 6.17%
  9. High Blood Cholesterol: 5 people, 6.17%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Captopril and Flonase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Captopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Flonase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Captopril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flonase and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on captopril and fluticasone propionate (the active ingredients of Captopril and Flonase, respectively), and Captopril and Flonase (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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