Captopril and Prinivil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Captopril (captopril) and Prinivil (lisinopril). Common drug interactions include bronchospasm among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Captopril and Prinivil. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Captopril?

Captopril has active ingredients of captopril. It is often used in high blood pressure. eHealthMe is studying from 17,438 Captopril users. Check the latest studies of Captopril.

What is Prinivil?

Prinivil has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 20,152 Prinivil users. Check the latest studies of Prinivil.



On May, 03, 2026

30 people who take Captopril and Prinivil together, and have interactions are studied.

Captopril and Prinivil drug interactions.

What are the common drug interactions of Captopril and Prinivil, by gender? *:

female:

  1. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  2. Depression
  3. Haemodynamic instability (disturbances in the blood movement in our body)
  4. Renal failure (kidney dysfunction)
  5. Renal failure acute (rapid kidney dysfunction)
  6. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Cardiac failure congestive
  9. Death
  10. Emotional distress

male:

  1. Anxiety
  2. Diarrhoea
  3. Fatigue (feeling of tiredness)
  4. Fear
  5. Injury
  6. Pain
  7. Periorbital cellulitis (inflammation and infection of the eyelid and the skin surrounding the eye)
  8. Platelet count decreased
  9. Renal failure (kidney dysfunction)
  10. Renal injury (kidney injury)

What are the common drug interactions of Captopril and Prinivil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Fall
  2. Cardiac failure congestive
  3. Congestive cardiomyopathy (weakening of heart muscle)

30-39:

  1. Blood urine present
  2. Diarrhoea
  3. Eye inflammation
  4. Periorbital cellulitis (inflammation and infection of the eyelid and the skin surrounding the eye)
  5. Platelet count decreased
  6. Weight decreased
  7. White blood cell count decreased
  8. Acute respiratory failure
  9. Asthenia (weakness)
  10. Blood phosphorus decreased

40-49:

  1. Anxiety
  2. Cardiac failure congestive
  3. Depression
  4. Emotional distress
  5. Fear
  6. Injury
  7. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  8. Pain
  9. Renal failure (kidney dysfunction)
  10. Renal injury (kidney injury)

50-59:

  1. Asthenia (weakness)
  2. Atelectasis (partial or complete collapse of the lung)
  3. Blood albumin decreased
  4. Blood calcium decreased
  5. Blood chloride increased
  6. Blood cholesterol increased
  7. Blood glucose increased
  8. Blood magnesium decreased
  9. Blood potassium increased
  10. Blood pressure systolic increased

60+:

  1. Metastases to liver (cancer spreads to liver)
  2. Pneumonia
  3. Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
  4. Burning sensation
  5. Flushing (the warm, red condition of human skin)
  6. Hypotension (abnormally low blood pressure)
  7. Renal failure (kidney dysfunction)
  8. Renal failure acute (rapid kidney dysfunction)
  9. Abdominal pain upper
  10. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)

What are the existing conditions these people have? *

  1. Depression: 8 people, 26.67%
  2. Pain: 6 people, 20.00%
  3. Breast Cancer: 5 people, 16.67%
  4. Stress And Anxiety: 3 people, 10.00%
  5. Diabetes: 3 people, 10.00%
  6. Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 2 people, 6.67%
  7. Cardiac Failure Congestive: 2 people, 6.67%
  8. Chest Pain: 2 people, 6.67%
  9. Collagen Disorder (infection and weakness of collagen): 2 people, 6.67%
  10. Insomnia (sleeplessness): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Captopril and Prinivil?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Captopril and Prinivil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Captopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prinivil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Captopril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prinivil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on captopril and lisinopril (the active ingredients of Captopril and Prinivil, respectively), and Captopril and Prinivil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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