Cardizem and Emend drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cardizem (diltiazem hydrochloride) and Emend (aprepitant). Common drug interactions include diarrhoea among females and abdominal pain among males.

The phase IV clinical study analyzes what interactions people have when they take Cardizem and Emend. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Cardizem?

Cardizem has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 28,014 Cardizem users. Check the latest studies of Cardizem.

What is Emend?

Emend has active ingredients of aprepitant. It is often used in nausea. eHealthMe is studying from 13,741 Emend users. Check the latest studies of Emend.

On Jul, 13, 2026

17 people who take Cardizem and Emend together, and have interactions are studied.

What are the common drug interactions of Cardizem and Emend, by gender? *:

female:

Diarrhoea
Haemoglobin decreased
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Muscular weakness (muscle weakness)
White blood cell count decreased
Alopecia (absence of hair from areas of the body)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dehydration (dryness resulting from the removal of water)
Depression

male:

Abdominal pain
Caecitis (inflammation of the cecum)
Vomiting
White blood cell count decreased
Dehydration (dryness resulting from the removal of water)
Dizziness postural
Full blood count decreased
Diarrhoea
Dizziness
Hypotension (abnormally low blood pressure)

What are the common drug interactions of Cardizem and Emend, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Diarrhoea
Haemoglobin decreased
Depression
Hair colour changes
Hair disorder
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal pain
Caecitis (inflammation of the cecum)
Carotid artery occlusion (artery blockage)
Cerebral infarction (less blood supply to brain resulting tissue damage)

What are the existing conditions these people have? *

Breast Cancer: 9 people, 52.94%
Insomnia (sleeplessness): 6 people, 35.29%
Neoplasm Malignant (cancer tumour): 3 people, 17.65%
Constipation: 3 people, 17.65%
High Blood Cholesterol: 2 people, 11.76%
Breast Cancer Female: 2 people, 11.76%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 11.76%
Rashes (redness): 1 person, 5.88%
Ovarian Cancer (cancer of ovary): 1 person, 5.88%
Oedema (fluid collection in tissue): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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