Casodex and Hydrocortisone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Casodex (bicalutamide) and Hydrocortisone (hydrocortisone). Common drug interactions include dyspnoea among females and pain among males.
The phase IV clinical study analyzes what interactions people have when they take Casodex and Hydrocortisone. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.
What is Casodex?
Casodex has active ingredients of bicalutamide. It is often used in prostate cancer. eHealthMe is studying from 10,725 Casodex users. Check the latest studies of Casodex.
What is Hydrocortisone?
Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.
79 people who take Casodex and Hydrocortisone together, and have interactions are studied.

What are the common drug interactions of Casodex and Hydrocortisone, by gender? *:
female:
- Dyspnoea (difficult or laboured respiration)
- Gait disturbance
- Metastases to bone (cancer spreads to bone)
- Neuralgia (pain in one or more nerves)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Osteonecrosis of jaw (death of bone of jaw)
- Pain
- Pain in jaw
- Scoliosis (a medical condition in which a person's spine is curved from side to side)
- Spinal osteoarthritis (joint cartilage loss in spine)
male:
- Pain
- Pain in jaw
- Anaemia (lack of blood)
- Chest pain
- Injury
- Malaise (a feeling of general discomfort or uneasiness)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Tooth infection
- Depression
- Constipation
What are the common drug interactions of Casodex and Hydrocortisone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Anxiety
- Bone erosion
- Constipation
- Dizziness
- Hot flush (sudden feelings of heat)
- Hypertension (high blood pressure)
- Impaired healing
- Injury
- Malaise (a feeling of general discomfort or uneasiness)
- Metastases to bone (cancer spreads to bone)
20-29:
n/a
30-39:
n/a
40-49:
- Back pain
- Metastases to bone (cancer spreads to bone)
- Neuralgia (pain in one or more nerves)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Pain
- Pain in jaw
- Purulent discharge (discharge that contains pus)
- Spinal osteoarthritis (joint cartilage loss in spine)
- Chest pain
- Constipation
50-59:
n/a
60+:
- Pain
- Anxiety
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Hot flush (sudden feelings of heat)
- Injury
- Purulent discharge (discharge that contains pus)
- Swelling
- Tooth infection
- Anaemia (lack of blood)
What are the existing conditions these people have? *
- Metastases To Bone (cancer spreads to bone): 20 people, 25.32%
- Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 17 people, 21.52%
- Gynecomastia (enlargement of the gland tissue of the male breast): 17 people, 21.52%
- Osteopenia (a condition where bone mineral density is lower than normal): 15 people, 18.99%
- Back Pain: 14 people, 17.72%
- Depression: 9 people, 11.39%
- Constipation: 9 people, 11.39%
- Sleep Disorder: 8 people, 10.13%
- Pain: 8 people, 10.13%
- Osteoporosis (bones weak and more likely to break): 8 people, 10.13%
* Approximation only. Some reports may have incomplete information.
Do you take Casodex and Hydrocortisone?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Casodex (10,725 reports)
- Hydrocortisone (40,425 reports)
Browse all drug interactions of Casodex and Hydrocortisone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Casodex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Hydrocortisone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Casodex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hydrocortisone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .
- Peng, C. C., Chen, C. Y., Chen, C. R., Chen, C. J., Shen, K. H., Chen, K. C., & Peng, R. Y., "Renal Damaging Effect Elicited by Bicalutamide Therapy Uncovered Multiple Action Mechanisms As Evidenced by the Cell Model", Scientific reports, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on bicalutamide and hydrocortisone (the active ingredients of Casodex and Hydrocortisone, respectively), and Casodex and Hydrocortisone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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