Ceftin and Sudafed drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ceftin (cefuroxime axetil) and Sudafed (pseudoephedrine hydrochloride). Common drug interactions include appendicitis among females and cardiac murmur among males.

The phase IV clinical study analyzes what interactions people have when they take Ceftin and Sudafed. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Ceftin?

Ceftin has active ingredients of cefuroxime axetil. It is often used in sinusitis. eHealthMe is studying from 4,333 Ceftin users. Check the latest studies of Ceftin.

What is Sudafed?

Sudafed has active ingredients of pseudoephedrine hydrochloride. It is often used in nasal congestion. eHealthMe is studying from 12,944 Sudafed users. Check the latest studies of Sudafed.

On Jul, 11, 2026

73 people who take Ceftin and Sudafed together, and have interactions are studied.

What are the common drug interactions of Ceftin and Sudafed, by gender? *:

female:

Appendicitis (inflammation of the appendix)
Aptyalism (deficiency or absence of saliva)
Asthma
Bone disorder
Bone erosion
Bone fragmentation
Bone pain
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
Cellulitis (infection under the skin)
Dental caries

male:

Cardiac murmur (an heart sound in valve abnormality)
Developmental delay
Cardiac tamponade (fluid accumulates in heart covering)
Cardiogenic shock (inadequate circulation of blood)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Pericardial effusion (fluid around the heart)
White blood cell count increased
Cardiac arrest
Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
Hypotension (abnormally low blood pressure)

What are the common drug interactions of Ceftin and Sudafed, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain
Ectopic pregnancy (a pregnancy in which the foetus develops outside the uterus, typically in a fallopian tube)
Haemoperitoneum (presence of blood in the peritoneal cavity)
Intermenstrual bleeding
Menstruation irregular

20-29:

Insomnia (sleeplessness)
Abdominal pain
Aggression
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Arthralgia (joint pain)
Blood amylase increased
Chest pain
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Depression
Dyspnoea (difficult or laboured respiration)

30-39:

Anaemia (lack of blood)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Depression
Emotional distress
Hepatitis (inflammation of the liver)
Inflammatory bowel disease
Intestinal haemorrhage (bleeding from intestine)
Intestinal obstruction
Irritable bowel syndrome
Panic attack

40-49:

Breath odour
Cardiac arrest
Constipation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Discomfort
Dry eye (lack of adequate tears)
Dry mouth
Dry skin
Dry throat

50-59:

Bone fragmentation
Bone pain
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
Cellulitis (infection under the skin)
Colitis ulcerative (inflammation of colon with ulcer)
Dental caries
Diarrhoea
Enteritis (inflammation of the small intestine)
Enterococcal infection
Escherichia infection (bacterial infection by escherichia coli)

60+:

Back pain
Cardiac failure
Compression fracture (fracture due to pressure caused by injury)
Drug hypersensitivity
Pneumonia

What are the existing conditions these people have? *

Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 24 people, 32.88%
Osteoporosis (bones weak and more likely to break): 24 people, 32.88%
Thrombocytopenia (decrease of platelets in blood): 11 people, 15.07%
Depression: 9 people, 12.33%
Mood Swings (an extreme or rapid change in mood): 8 people, 10.96%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 8.22%
Acne (skin problems that cause pimples): 5 people, 6.85%
Asthma: 4 people, 5.48%

* Approximation only. Some reports may have incomplete information.

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