Ceftriaxone and Ibrin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ceftriaxone (ceftriaxone sodium) and Ibrin (fibrinogen, i-125). Common drug interactions include thrombocytopenia among females and pericardial effusion among males.
The phase IV clinical study analyzes what interactions people have when they take Ceftriaxone and Ibrin. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.
What is Ceftriaxone?
Ceftriaxone has active ingredients of ceftriaxone sodium. It is often used in typhoid fever. eHealthMe is studying from 40,991 Ceftriaxone users. Check the latest studies of Ceftriaxone.
What is Ibrin?
Ibrin has active ingredients of fibrinogen, i-125. eHealthMe is studying from 470 Ibrin users. Check the latest studies of Ibrin.
22 people who take Ceftriaxone and Ibrin together, and have interactions are studied.

What are the common drug interactions of Ceftriaxone and Ibrin, by gender? *:
female:
- Thrombocytopenia (decrease of platelets in blood)
- Mucosal inflammation (infection of mucous membrane)
- Coagulopathy (blood's ability to clot is impaired)
- Hepatic failure (liver failure)
- Pulmonary embolism (blockage of the main artery of the lung)
- Renal failure acute (rapid kidney dysfunction)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
- Dyspnoea (difficult or laboured respiration)
- Hypotension (abnormally low blood pressure)
male:
- Pericardial effusion (fluid around the heart)
- Pulmonary embolism (blockage of the main artery of the lung)
- Hypotension (abnormally low blood pressure)
- Septic shock (shock due to blood infection)
- Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull)
- Intraventricular haemorrhage (intraventricular bleeding)
- Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
- Blood bilirubin increased
- Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
What are the common drug interactions of Ceftriaxone and Ibrin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Coagulopathy (blood's ability to clot is impaired)
- Hepatic failure (liver failure)
- Pneumonia
- Pulmonary embolism (blockage of the main artery of the lung)
- Renal failure acute (rapid kidney dysfunction)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
- Thrombocytopenia (decrease of platelets in blood)
- Dyspnoea (difficult or laboured respiration)
- Hypotension (abnormally low blood pressure)
40-49:
- Alanine aminotransferase increased
- Blood triglycerides increased
- C-reactive protein increased
- Haemoglobin decreased
- High density lipoprotein decreased
- Hyperuricaemia (level of uric acid in the blood that is abnormally high)
- Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
- Hypokalaemia (low potassium)
- Leukopenia (less number of white blood cells in blood)
- Low density lipoprotein increased (cholesterol increased in blood)
50-59:
- Pneumonia
- Thrombocytopenia (decrease of platelets in blood)
- Pericardial effusion (fluid around the heart)
- Pulmonary embolism (blockage of the main artery of the lung)
- Mucosal inflammation (infection of mucous membrane)
- Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull)
- Intraventricular haemorrhage (intraventricular bleeding)
- Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
60+:
- Hypotension (abnormally low blood pressure)
- Septic shock (shock due to blood infection)
What are the existing conditions these people have? *
- Constipation: 10 people, 45.45%
- Fever: 9 people, 40.91%
- Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 8 people, 36.36%
- Anaemia (lack of blood): 8 people, 36.36%
- Urination - Excessive Volume: 6 people, 27.27%
- Procedural Pain: 5 people, 22.73%
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 5 people, 22.73%
- Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 5 people, 22.73%
- Blood Bilirubin Increased: 5 people, 22.73%
- Breast Cancer Metastatic: 5 people, 22.73%
* Approximation only. Some reports may have incomplete information.
Do you take Ceftriaxone and Ibrin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Ceftriaxone (40,991 reports)
- Ibrin (470 reports)
Browse all drug interactions of Ceftriaxone and Ibrin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ceftriaxone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ibrin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ceftriaxone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ibrin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on ceftriaxone sodium and fibrinogen, i-125 (the active ingredients of Ceftriaxone and Ibrin, respectively), and Ceftriaxone and Ibrin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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