Celexa and Hycodan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Celexa (citalopram hydrobromide) and Hycodan (homatropine methylbromide; hydrocodone bitartrate). Common drug interactions include keratoconjunctivitis sicca among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Celexa and Hycodan. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Celexa?

Celexa has active ingredients of citalopram hydrobromide. It is often used in depression. eHealthMe is studying from 56,390 Celexa users. Check the latest studies of Celexa.

What is Hycodan?

Hycodan has active ingredients of homatropine methylbromide; hydrocodone bitartrate. It is often used in cough. eHealthMe is studying from 769 Hycodan users. Check the latest studies of Hycodan.



On Jul, 18, 2026

23 people who take Celexa and Hycodan together, and have interactions are studied.

Celexa and Hycodan drug interactions.

What are the common drug interactions of Celexa and Hycodan, by gender? *:

female:

  1. Keratoconjunctivitis sicca (inflammation of the conjunctiva and cornea of the eye with decreased tears)
  2. Lung disorder (lung disease)
  3. Lymphadenopathy (disease or enlargement of lymph nodes)
  4. Neuropathy peripheral (surface nerve damage)
  5. Oral herpes (viral infection of mouth)
  6. Palpitations (feelings or sensations that your heart is pounding or racing)
  7. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  8. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)
  9. Synovial cyst (cyst of joint filled with synovial fluid)
  10. Tachycardia (a heart rate that exceeds the range of 100 beats/min)

male:

  1. Back pain
  2. Increased upper airway secretion
  3. Muscle strain (an injury to a muscle in which the muscle fibres tear)
  4. Pneumonia
  5. Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Celexa and Hycodan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Hodgkin's disease (cancer originating from white blood cells)
  2. Impetigo (contagious skin infection)
  3. Keratoconjunctivitis sicca (inflammation of the conjunctiva and cornea of the eye with decreased tears)
  4. Lacrimation increased
  5. Lung disorder (lung disease)
  6. Lymphadenopathy (disease or enlargement of lymph nodes)
  7. Neuropathy peripheral (surface nerve damage)
  8. Oral herpes (viral infection of mouth)
  9. Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
  10. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)

30-39:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

40-49:

  1. Anaemia (lack of blood)
  2. Asthma
  3. Chills (felling of cold)
  4. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  5. Confusional state
  6. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  7. Dyspnoea (difficult or laboured respiration)
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Generalised oedema (swelling all over the body)
  10. Hypertension (high blood pressure)

50-59:

  1. Skin hypertrophy (skin cells enlarges)
  2. Skin hypopigmentation (loss of skin colour)
  3. Skin lesion
  4. Skin tightness
  5. Xerosis (abnormal dryness of the skin or mucus membranes)
  6. Back pain
  7. Headache (pain in head)
  8. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  9. Influenza like illness
  10. Muscle strain (an injury to a muscle in which the muscle fibres tear)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Anaemia (lack of blood)
  3. Pneumonia
  4. Acidosis (build-up of carbon dioxide in the blood)
  5. Acute myocardial infarction (acute heart attack)
  6. Acute pulmonary oedema (sudden deposit of fluid in the lung))
  7. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  8. Angioplasty
  9. Arthralgia (joint pain)
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints)

What are the existing conditions these people have? *

  1. Oropharyngeal Pain: 6 people, 26.09%
  2. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 6 people, 26.09%
  3. Pain: 3 people, 13.04%
  4. Stress And Anxiety: 2 people, 8.70%
  5. Nausea (feeling of having an urge to vomit): 2 people, 8.70%
  6. Asthma: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Celexa and Hycodan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Celexa and Hycodan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Celexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hycodan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Celexa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hycodan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on citalopram hydrobromide and homatropine methylbromide; hydrocodone bitartrate (the active ingredients of Celexa and Hycodan, respectively), and Celexa and Hycodan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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