Celexa and Limbitrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Celexa (citalopram hydrobromide) and Limbitrol (amitriptyline hydrochloride; chlordiazepoxide). Common drug interactions include blood triglycerides increased among females and cardiomegaly among males.

The phase IV clinical study analyzes what interactions people have when they take Celexa and Limbitrol. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Celexa?

Celexa has active ingredients of citalopram hydrobromide. It is often used in depression. eHealthMe is studying from 56,390 Celexa users. Check the latest studies of Celexa.

What is Limbitrol?

Limbitrol has active ingredients of amitriptyline hydrochloride; chlordiazepoxide. It is often used in stress and anxiety. eHealthMe is studying from 378 Limbitrol users. Check the latest studies of Limbitrol.



On Jul, 17, 2026

15 people who take Celexa and Limbitrol together, and have interactions are studied.

Celexa and Limbitrol drug interactions.

What are the common drug interactions of Celexa and Limbitrol, by gender? *:

female:

  1. Blood triglycerides increased
  2. Dependence
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  5. Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
  6. Drug addiction
  7. Herpes zoster
  8. Hyperglycaemia (high blood sugar)
  9. Lipids increased (excess lipid in body)
  10. Rash

male:

  1. Cardiomegaly (increased size of heart than normal)
  2. Chest pain
  3. Fall
  4. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  5. Hypoaesthesia (reduced sense of touch or sensation)
  6. Joint swelling
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Myalgia (muscle pain)
  9. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  10. Neck pain

What are the common drug interactions of Celexa and Limbitrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Nausea (feeling of having an urge to vomit)
  2. Pancreatitis (inflammation of pancreas)
  3. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  4. Polydipsia (excessive thirst)
  5. Polyuria (production of too much dilute urine)
  6. Rash erythematous (redness of the skin)
  7. Renal colic (renal pain)
  8. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  9. Sweating increased (excess sweating)
  10. Syncope (loss of consciousness with an inability to maintain postural tone)

50-59:

  1. Blood glucose increased
  2. Blood triglycerides increased
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Hyperglycaemia (high blood sugar)
  5. Lipids increased (excess lipid in body)
  6. Type 2 diabetes mellitus

60+:

  1. Abdominal distension
  2. Acquired cardiac septal defect (hole in the heart)
  3. Bradycardia (abnormally slow heart action)
  4. Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
  5. Cardiac arrest
  6. Cardiac failure congestive
  7. Cardiac valve disease (heart valve disease)
  8. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  9. Cardiogenic shock (inadequate circulation of blood)
  10. Cardiomegaly (increased size of heart than normal)

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 33.33%
  2. Migraine (headache): 2 people, 13.33%
  3. Sleep Disorder: 1 person, 6.67%
  4. Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 6.67%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 6.67%
  6. Psoriasis (immune-mediated disease that affects the skin): 1 person, 6.67%
  7. Pain: 1 person, 6.67%
  8. Muscle Spasms (muscle contraction): 1 person, 6.67%
  9. Hot Flush (sudden feelings of heat): 1 person, 6.67%
  10. High Blood Pressure: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Celexa and Limbitrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Celexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Limbitrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Celexa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Limbitrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on citalopram hydrobromide and amitriptyline hydrochloride; chlordiazepoxide (the active ingredients of Celexa and Limbitrol, respectively), and Celexa and Limbitrol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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