Celexa and Naloxone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Celexa (citalopram hydrobromide) and Naloxone (naloxone hydrochloride). Common drug interactions include nasal congestion among females and abscess among males.
The phase IV clinical study analyzes what interactions people have when they take Celexa and Naloxone. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.
What is Celexa?
Celexa has active ingredients of citalopram hydrobromide. It is often used in depression. eHealthMe is studying from 56,390 Celexa users. Check the latest studies of Celexa.
What is Naloxone?
Naloxone has active ingredients of naloxone hydrochloride. eHealthMe is studying from 6,425 Naloxone users. Check the latest studies of Naloxone.
35 people who take Celexa and Naloxone together, and have interactions are studied.

What are the common drug interactions of Celexa and Naloxone, by gender? *:
female:
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Open wound
- Osteomyelitis (infection of bone)
- Osteonecrosis of jaw (death of bone of jaw)
- Osteosclerosis (an elevation in bone density)
- Pain
- Pain in jaw
- Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
- Pathological fracture (broken bone caused by disease)
- Primary sequestrum (piece of dead bone that has become separated during the process of necrosis from normal/sound bone)
male:
- Abscess (pus)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Facial pain
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Hyperlipidaemia (presence of excess lipids in the blood)
- Impetigo (contagious skin infection)
- Injury
- Jaw fracture
- Metastases to bone (cancer spreads to bone)
- Metastases to liver (cancer spreads to liver)
What are the common drug interactions of Celexa and Naloxone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Acute graft versus host disease in intestine (acute complication in intestine following an allogeneic tissue/blood transplant)
- Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
- Delirium (wild excitement)
- Pyrexia (fever)
- Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot)
- Cardiac arrest
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
50-59:
- Bacteraemia (presence of bacteria in the blood)
- Blood albumin decreased
- Death
- Disease progression
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Hiv infection
- Hypokalaemia (low potassium)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Local swelling (swelling at the site of some application of substance or injury)
- Lung cancer metastatic (lung cancer spreads to other parts)
60+:
- Rib fracture
- Injury
- Erythema (redness of the skin)
- Exposed bone in jaw
- Facial nerve disorder (disease of face nerve)
- Facial pain
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
- Hyperlipidaemia (presence of excess lipids in the blood)
- Impetigo (contagious skin infection)
- Jaw fracture
What are the existing conditions these people have? *
- High Blood Pressure: 4 people, 11.43%
- Breast Cancer Metastatic: 4 people, 11.43%
- Multiple Myeloma (cancer of the plasma cells): 4 people, 11.43%
- Stress And Anxiety: 4 people, 11.43%
- Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 3 people, 8.57%
- Pain: 3 people, 8.57%
- Nausea (feeling of having an urge to vomit): 3 people, 8.57%
- Constipation: 3 people, 8.57%
- Drug Exposure During Pregnancy: 3 people, 8.57%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.57%
* Approximation only. Some reports may have incomplete information.
Do you take Celexa and Naloxone?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Celexa and Naloxone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Celexa:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Naloxone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Celexa and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Naloxone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hosseini, S. H., & Ahmadi, A., "Peripheral edema occurring during treatment with risperidone combined with citalopram", Case reports in medicine, 2012 Jan .
- Hosseini, S. H., & Ahmadi, A., "Peripheral edema occurring during treatment with risperidone combined with citalopram", Case reports in medicine, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on citalopram hydrobromide and naloxone hydrochloride (the active ingredients of Celexa and Naloxone, respectively), and Celexa and Naloxone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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