Centrum and Sandostatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Sandostatin (octreotide acetate). Common drug interactions include hypertension among females and back pain among males.

The phase IV clinical study analyzes what interactions people have when they take Centrum and Sandostatin. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

What is Sandostatin?

Sandostatin has active ingredients of octreotide acetate. It is often used in acromegaly. eHealthMe is studying from 46,793 Sandostatin users. Check the latest studies of Sandostatin.



On Jul, 17, 2026

73 people who take Centrum and Sandostatin together, and have interactions are studied.

Centrum and Sandostatin drug interactions.

What are the common drug interactions of Centrum and Sandostatin, by gender? *:

female:

  1. Hypertension (high blood pressure)
  2. Body temperature decreased
  3. Injection site pain
  4. Pruritus (severe itching of the skin)
  5. Respiratory rate increased (excess breathing rate/min)
  6. Scratch
  7. Chills (felling of cold)
  8. Hepatic enzyme increased
  9. Pyrexia (fever)
  10. Heart rate increased

male:

  1. Back pain
  2. Weight decreased
  3. Injection site mass
  4. Metastases to pelvis (cancer spreads to pelvis)
  5. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  6. Injection site pain
  7. Flushing (the warm, red condition of human skin)
  8. Intestinal obstruction
  9. Abdominal adhesions (inflammation of abdomen)
  10. Abdominal pain

What are the common drug interactions of Centrum and Sandostatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain
  2. Confusional state
  3. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  4. Nausea (feeling of having an urge to vomit)
  5. Right ventricular failure (right half of the heart fails to work)
  6. Septic shock (shock due to blood infection)
  7. Skin wound
  8. Somnolence (a state of near-sleep, a strong desire for sleep)
  9. Vomiting

40-49:

n/a

50-59:

  1. Scratch
  2. Pruritus generalised (generalized itching)
  3. Abdominal pain upper
  4. Abnormal faeces (abnormal stool)
  5. Back pain
  6. Blood chromogranin a increased
  7. Drug ineffective
  8. Gastric cancer (stomach cancer)
  9. Gastric cancer stage iii (the tumour has invaded nearby organs, such as the liver, colon, or spleen. cancer cells have not spread to lymph nodes or to distant organs)
  10. Kidney infection

60+:

  1. Weight decreased
  2. Diarrhoea
  3. Injection site mass
  4. Asthenia (weakness)
  5. Cough
  6. Metastases to pelvis (cancer spreads to pelvis)
  7. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  8. Blood pressure systolic increased
  9. Nausea (feeling of having an urge to vomit)
  10. Flushing (the warm, red condition of human skin)

What are the existing conditions these people have? *

  1. Carcinoid Syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction): 10 people, 13.70%
  2. Metastatic Carcinoid Tumor: 7 people, 9.59%
  3. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 6 people, 8.22%
  4. Pancreatic Neuroendocrine Tumor: 5 people, 6.85%
  5. Neuroendocrine Tumor: 5 people, 6.85%
  6. Neuroendocrine Carcinoma (cancer tumour that arise from cells of the endocrine (hormonal) and nervous systems): 5 people, 6.85%
  7. Renal Cell Carcinoma (a kidney cancer): 4 people, 5.48%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 5.48%
  9. Migraine (headache): 4 people, 5.48%
  10. High Blood Cholesterol: 4 people, 5.48%

* Approximation only. Some reports may have incomplete information.

Do you take Centrum and Sandostatin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Centrum and Sandostatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Centrum:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sandostatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Centrum and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sandostatin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e and octreotide acetate (the active ingredients of Centrum and Sandostatin, respectively), and Centrum and Sandostatin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: