Methylin and Pancytopenia - a phase IV clinical study of FDA data
Summary:
Pancytopenia is reported as a side effect among people who take Methylin (methylphenidate hydrochloride), especially for people who are female, 60+ old, also take Aredia, and have Hypercalcaemia of malignancy.
The phase IV clinical study analyzes which people have Pancytopenia when taking Methylin. It is created by eHealthMe based on reports of 909 people who have side effects when taking Methylin from the FDA, and is updated regularly.
What is Methylin?
Methylin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 1,116 Methylin users. Check the latest studies of Methylin.
What is Pancytopenia?
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets) is found to be associated with 1,793 drugs and 2,431 conditions by eHealthMe. Check the latest studies of Pancytopenia.
909 people reported to have side effects when taking Methylin.
Among them, 19 people (2.09%) have Pancytopenia.

Among these 19 people:
What is the gender of people who have Pancytopenia when taking Methylin? *
- female: 68.42 %
- male: 31.58 %
What is the age of people who have Pancytopenia when taking Methylin? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 31.58 %
- 50-59: 5.26 %
- 60+: 63.16 %
What are other drugs people take besides Methylin? *
- Zometa: 19 people, 100.00%
- Ativan: 19 people, 100.00%
- Aredia: 19 people, 100.00%
- Levaquin: 18 people, 94.74%
- Wellbutrin: 18 people, 94.74%
- Trimox: 13 people, 68.42%
- Ms Contin: 13 people, 68.42%
- Lovastatin: 13 people, 68.42%
- Prilosec: 13 people, 68.42%
- Lasix: 13 people, 68.42%
What are other side effects people have besides Pancytopenia? *
- Weakness: 19 people, 100.00%
- Bone Disorder: 19 people, 100.00%
- Pain: 19 people, 100.00%
- High Blood Pressure: 19 people, 100.00%
- Anaemia (lack of blood): 19 people, 100.00%
- Nausea And Vomiting: 19 people, 100.00%
- Infection: 19 people, 100.00%
- Back Pain: 19 people, 100.00%
- Swallowing Difficulty: 19 people, 100.00%
- Intervertebral Disc Protrusion (spinal disc protrusion): 18 people, 94.74%
What are the existing conditions these people have? *
- Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 13 people, 68.42%
- Multiple Myeloma (cancer of the plasma cells): 6 people, 31.58%
- Metastases To Bone (cancer spreads to bone): 6 people, 31.58%
* Approximation only. Some reports may have incomplete information.
Do you take Methylin and have Pancytopenia?
- Check whether Pancytopenia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Methylin:
- Methylin (1,116 reports)
Pancytopenia treatments and more:
- Pancytopenia (69,290 reports)
How severe was Pancytopenia and when was it recovered:
Expand to all the drugs that have ingredients of methylphenidate hydrochloride:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Methylin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Pancytopenia:
- Pancytopenia (1,793 drugs)
Browse all the conditions that are associated with Pancytopenia:
- Pancytopenia (2,431 conditions)
Related publications that referenced our studies
- Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
- Yektas ?, Samurcu ND, Tufan AE, "Loss of Eyebrows (Madarosis) After Use of Long-Acting Methylphenidate: Case Report", Journal of Clinical Psychopharmacology, 2017 Aug .
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Adak, I., & Coskun, M. , "Symptomatic cholelithiasis associated with combined use of methylphenidate and fluoxetine in an otherwise healthy adolescent girl", Psychiatry and Clinical Psychopharmacology, 2014 Jan .
- Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .
- Erden M, Gulcan E, Bilen A, Bilen Y, Uyanik A, Keles M, "Pancytopen? a and Seps? s due to Meropenem: A Case Report", Tropical Journal of Pharmaceutical Research, 2013 Jan .
- Yalcin O, Aslan AA, Sari BA, Turkbay T, "Possible methylphenidate related hoarseness and disturbances of voice quality: two pediatric cases", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012 Sep .
- Lufi D, Bucherman M, Akita M, Cohen R, Sibani C, "The effect of methylphenidate on speech patterns of children with attention deficit disorder", Journal of Behavioral Health, 2012 Jan .
- Coskun M, Adak I, "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2017 Oct .
- Yektas ?, Samurcu ND, Tufan AE, "Loss of Eyebrows (Madarosis) After Use of Long-Acting Methylphenidate: Case Report", Journal of Clinical Psychopharmacology, 2017 Aug .
- Ate? ?, Arikan MF, Kaplan M, Altay M, "Hydroxyzine induced pancytopenia and petechial rashes: a rare complication", Journal Of Contemporary Medicine, 2017 Jan .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Adak, I., & Coskun, M. , "Symptomatic cholelithiasis associated with combined use of methylphenidate and fluoxetine in an otherwise healthy adolescent girl", Psychiatry and Clinical Psychopharmacology, 2014 Jan .
- Coskun, M., & Adak, I. , "Excessive and frequent menstrual bleeding with methylphenidate in an adolescent girl with attention-deficit hyperactivity disorder", Journal of clinical psychopharmacology, 2014 Jan .
- Erden M, Gulcan E, Bilen A, Bilen Y, Uyanik A, Keles M, "Pancytopen? a and Seps? s due to Meropenem: A Case Report", Tropical Journal of Pharmaceutical Research, 2013 Jan .
- Yalcin O, Aslan AA, Sari BA, Turkbay T, "Possible methylphenidate related hoarseness and disturbances of voice quality: two pediatric cases", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012 Sep .
- Lufi D, Bucherman M, Akita M, Cohen R, Sibani C, "The effect of methylphenidate on speech patterns of children with attention deficit disorder", Journal of Behavioral Health, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on methylphenidate hydrochloride (the active ingredients of Methylin) and Methylin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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