Cephalexin and Vibramycin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cephalexin (cephalexin) and Vibramycin (doxycycline). Common drug interactions include abdominal pain lower among females and cerebral infarction among males.
The phase IV clinical study analyzes what interactions people have when they take Cephalexin and Vibramycin. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Cephalexin?
Cephalexin has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 30,580 Cephalexin users. Check the latest studies of Cephalexin.
What is Vibramycin?
Vibramycin has active ingredients of doxycycline. It is often used in acne. eHealthMe is studying from 1,692 Vibramycin users. Check the latest studies of Vibramycin.
11 people who take Cephalexin and Vibramycin together, and have interactions are studied.

What are the common drug interactions of Cephalexin and Vibramycin, by gender? *:
female:
- Abdominal pain lower
- Hypoaesthesia (reduced sense of touch or sensation)
- Hypokinesia (decreased bodily movement)
- Hypotension (abnormally low blood pressure)
- Acute myocardial infarction (acute heart attack)
- Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
- Anaemia (lack of blood)
- Anxiety
- Aortic thrombosis (formation of a blood clot inside aorta)
- Aortic valve incompetence
male:
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Chronic kidney disease
- Dizziness
- Renal failure (kidney dysfunction)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
What are the common drug interactions of Cephalexin and Vibramycin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
30-39:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Gastroenteritis (inflammation of stomach and intestine)
40-49:
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
50-59:
n/a
60+:
- Back pain
- Hypertension (high blood pressure)
- Ascites (accumulation of fluid in the abdominal cavity)
- Asthenia (weakness)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
- Atrioventricular block first degree (heart block first degree)
- Bradycardia (abnormally slow heart action)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cardiac failure congestive
What are the existing conditions these people have? *
- Insomnia (sleeplessness): 2 people, 18.18%
- Cardiac Disorder: 2 people, 18.18%
- Depression: 2 people, 18.18%
- Pain: 2 people, 18.18%
- Weakness: 1 person, 9.09%
- Constipation: 1 person, 9.09%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%
- Gout (uric acid crystals building up in the body): 1 person, 9.09%
- Headache (pain in head): 1 person, 9.09%
- Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Cephalexin and Vibramycin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Cephalexin (30,580 reports)
- Vibramycin (1,692 reports)
Browse all drug interactions of Cephalexin and Vibramycin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cephalexin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Vibramycin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cephalexin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vibramycin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Agrawal A, Rao M, Jasdanwala S, Mathur A, Eng M, "Cephalexin Induced Cholestatic Jaundice", Case reports in gastrointestinal medicine, 2014 Aug .
- Dmour HH, Zayadeen AR, Shawagfeh JS, "Effect of Long Term Prophylaxis of Antimalarial Drug (Doxycycline) on Liver Span by Ultrasound", Middle East Journal of Internal Medicine, 2013 Jan .
- Agrawal A, Rao M, Jasdanwala S, Mathur A, Eng M, "Cephalexin Induced Cholestatic Jaundice", Case reports in gastrointestinal medicine, 2014 Aug .
- Dmour HH, Zayadeen AR, Shawagfeh JS, "Effect of Long Term Prophylaxis of Antimalarial Drug (Doxycycline) on Liver Span by Ultrasound", Middle East Journal of Internal Medicine, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on cephalexin and doxycycline (the active ingredients of Cephalexin and Vibramycin, respectively), and Cephalexin and Vibramycin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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