Cerezyme and Oxycontin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cerezyme (imiglucerase) and Oxycontin (oxycodone hydrochloride). Common drug interactions include rheumatoid arthritis among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Cerezyme and Oxycontin. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Cerezyme?

Cerezyme has active ingredients of imiglucerase. eHealthMe is studying from 6,451 Cerezyme users. Check the latest studies of Cerezyme.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 212,533 Oxycontin users. Check the latest studies of Oxycontin.



On Aug, 09, 2026

23 people who take Cerezyme and Oxycontin together, and have interactions are studied.

Cerezyme and Oxycontin drug interactions.

What are the common drug interactions of Cerezyme and Oxycontin, by gender? *:

female:

  1. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  2. Abdominal mass (localized enlargement or swelling in the human abdomen)
  3. Arthralgia (joint pain)
  4. Cystitis (inflammation of the wall of the bladder)
  5. Joint swelling
  6. Pathological fracture (broken bone caused by disease)
  7. Polyp colorectal
  8. Upper limb fracture
  9. Colon adenoma (non cancerous epithelial colon tumour having a glandular origin and structure)
  10. Lower respiratory tract infection

male:

  1. Arthralgia (joint pain)
  2. Bone pain
  3. Aortic disorder
  4. Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
  5. Cardiac valve disease (heart valve disease)
  6. Chest discomfort
  7. Confusional state
  8. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  9. Dysplasia (enlargement of an organ or tissue)
  10. Herpes zoster

What are the common drug interactions of Cerezyme and Oxycontin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Central line infection (infection by central line in icu)
  2. Endocarditis (inflammation in heart muscle)
  3. Generalised oedema (swelling all over the body)
  4. Infection
  5. Splenomegaly (enlargement of spleen)
  6. Abdominal pain
  7. Arthralgia (joint pain)
  8. Bone pain
  9. Confusional state
  10. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

30-39:

n/a

40-49:

  1. Chest discomfort
  2. Night sweats (sweating in night)
  3. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  4. Urinary tract infection

50-59:

  1. Fatigue (feeling of tiredness)
  2. Aortic disorder
  3. Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
  4. Bone pain
  5. Cardiac valve disease (heart valve disease)
  6. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  7. Dysplasia (enlargement of an organ or tissue)
  8. Herpes zoster
  9. Immune system disorder
  10. Influenza like illness

60+:

  1. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  2. Abdominal mass (localized enlargement or swelling in the human abdomen)
  3. Parkinson's disease
  4. Pneumonia
  5. Scapula fracture (a fracture of the scapula, the shoulder blade)
  6. Upper respiratory tract infection
  7. Cystitis (inflammation of the wall of the bladder)
  8. Pathological fracture (broken bone caused by disease)
  9. Polyp colorectal
  10. Upper limb fracture

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 8 people, 34.78%
  2. High Blood Pressure: 6 people, 26.09%
  3. Osteoporosis (bones weak and more likely to break): 3 people, 13.04%
  4. Depression: 3 people, 13.04%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cerezyme and Oxycontin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cerezyme:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Oxycontin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cerezyme and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycontin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on imiglucerase and oxycodone hydrochloride (the active ingredients of Cerezyme and Oxycontin, respectively), and Cerezyme and Oxycontin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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